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Ultra Low-Level Detection of Perfluoroalkyl Substances (PFASs) using the PFC Analysis Kit

19 Jun 2016

This application note demonstrates the use of the PFC Analysis Kit on the ACQUITY UPLC® I-Class System and the limits of detection afforded for PFASs analyzed on the Xevo® TQ-S. Perfluoroalkyl substances (PFASs) encompass a range of fully fluorinated alkyl compounds, typically with an anionic end group. PFASs have been implemented in a range of consumer goods and as a result of their widespread use and subsequent leaching, they have been found in various environmental and biological samples.

Xevo TQ-S

Waters

Xevo TQ-S tandem quadrupole mass spectrometer - designed for the most demanding quantitative UPLC/MS/MS applications. The ultimate in tandem quadrupole performance allows you to achieve unrivalled sensitivity and robustness, available to everyone due to the accessibility of the Xevo platform. The Xevo TQ-S gives you class leading sensitivity and robustness, qualitative information when you need it most and accelerated method development for sensitive and robust methods. Reducing complexity, increasing ease of use, and ensuring the correct result every time.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Low Extractable LevelsSample Preparation
Ultra Low-Level Detection of Perfluoroalkyl Substances (PFASs) using the PFC Analysis Kit