ResourceSeparations

Ultra-high speed separation of food additives in a soft drink

14 Mar 2022

In this application note, the usefulness of an X-PressPak V-C (2.0 mm I.D. x 50 mm L.) packed with 2 μm diameter packing material for the ultra-high speed separation of food additives was examined. A 4λ−UV detector was used for the simultaneous monitoring of these additives at four different wavelengths. The results were examined to determine whether the performance of the column and chromatography system exceeds those of conventional HPLC.

LC-4000 Series Integrated HPLC and UHPLC Systems

JASCO (USA)

The LC-4000 Series is the latest in a long history of innovative HPLC systems developed by JASCO reaching all the way back to the start of commercial HPLC in the early 1970s. The concept of the integrated LC-4000 series HPLC provides key separation platforms at 50MPa, 70MPa and 130MPa which correspond to conventional HPLC, the increasingly popular Rapid Analysis (RHPLC) and sub 2um UHPLC, respectively. Each platform is supplied with a dedicated pump and autosampler matched to the operating pressure and all three platforms share common detectors optimized for high-speed 100Hz acquisition and the narrow peak shapes common to both RHPLC and UHPLC. Features 300mm wide footprint Each system component is completely stackable into a modest height The system is fully integrated with complete system monitoring All user replaceable components are accessible through the front panel Vertical leak/drain system to channel away solvent Integrated earthquake securing option All detectors include 100Hz acquistion with interchangeable flowcells Preparative HPLC Systems The LC-4000 preparative HPLC systems includes three platform options Up to 20mL/min for columns up to 21.2mm ID Up to 50mL/min for columns up to 3cm ID Up to 120mL/min for columns up to 5cm ID

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Food AdditivesFood TestingFood testing refers to a variety experiments including PCR, mass spectrometry, processing, QuEChERS, analyzing and Kjeldahl.
Ultra-high speed separation of food additives in a soft drink