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The Malvern Nanoparticle Tracking Analysis 1000 Publications Review Part Six: Drug Nanocarriers
21 Apr 2016This white paper discusses the role of Nanoparticle Tracking Analysis (NTA) in nanomedicine and reviews the specific mechanisms by which such nanoparticles are designed and formulated. Nanoparticles, and many of their subsets, have been revealed to have important biomedical applications; one in particular being drug delivery. Particles can be engineered to specifically target diseased cells, such as cancer cells, allowing for targeted drug therapy with reduced collateral effects.
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Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.NanotechnologyNanotechnology, or nanotech, is an engineering technique using molecular scale functional systems. Applications of nanotechnology include medicine and medical devices, electronics, air and water purification, food science and energy production.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Drug DeliveryDrug Delivery refers to dosage form, route of administration, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect. Drug delivery is often approached via the biopharmaceutical or small molecule drug's formulation, but it may also involve medical devices or drug-device combination products. Considerations include instrumentation, software and services. NanoparticlesNanoparticles are between 1-100nm in size. Nanoparticles can be used for a wide variety of applications including biomedical, catalysis and electronics.Engineered NanoparticlesDrug DevelopmentDrug development refers to the process of bringing a new drug to market.