Research on particle sizing dispersion methods for Domperidone API using a laser particle size analyzer
6 Feb 2023In this application note, a Bettersizer 2600 was used to systematically study the particle size distribution of Domperidone API. The application note investigates the impact of dispersing intensity on the particle size analysis, including different air pressures of dry dispersion, different stirring speeds, and ultrasonic dispersing time of wet dispersion.
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Bettersizer 2600
Bettersize Instruments LtdParticle Size Analyzer (Laser Diffraction + Dynamic Imaging)
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Drug DeliveryDrug Delivery refers to dosage form, route of administration, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect. Drug delivery is often approached via the biopharmaceutical or small molecule drug's formulation, but it may also involve medical devices or drug-device combination products. Considerations include instrumentation, software and services. RegulatoryPharmaceutical regulations impact on all areas of drug development, manufacture and control and supply. Services are provided from the early stages of drug development and clinical trials through to dossier submission, approval and marketing. Regulatory also includes submission of analytical studies from the pharmaceutical product and safety. Particle Size AnalysisParticle size analysis describes the size distributions from sub-nanometer to millimeter of particulate samples. Size is an important physical property and the technique is often utilized in a range of industries, such as chemical, environmental and agriculture.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.