ResourceLife Sciences
Refining charge variant analysis of mAbs with the Agilent 1290 Infinity II Bio LC System
27 Jun 2021Charge variant analysis is a demanding application for applied liquid chromatography systems due to the use of highly corrosive buffer salts in combination with very shallow gradients for optimal separation. This application note demonstrates the analysis of charge variants for trastuzumab and the NISTmAb reference standard.
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Agilent 1290 Infinity II Bio LC System
Agilent TechnologiesThe 1290 Infinity II Bio LC System is a UHPLC, binary or quaternary ,- consisting of biocompatible material for use in biopharma (e.g., critical quality attributes) and other applications utilizing high salt and extreme pH conditions. Biocompatibility ensures the integrity of your biomolecules and robustness of the system.