Recordings of Action Potentials in Mouse ES Cell-Derived Cor.At® Cardiomyocytes on Nanion's Patchliner®
4 Feb 2011Axiogenesis is a provider of pure mouse embryonic stem cell-derived cardiomyocytes. These cardiomyocytes have been evaluated with Nanion’s automated patch clamp platforms the Port-a-Patch® and the Patchliner®. The aim of this study was to show that the Patchliner®, Nanion´s planar patch clamp device for increased throughput, can be used for studies investigating compounds which exhibit chronotropic or arrhythmic effects.
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Patchliner
Nanion Technologies GmbHThe Patchliner is a fully automated patch clamp system which records from either 4 or 8 cells simultaneously. The HEKA EPC10 amplifiers, full control over the pipette speed, ability to change protocols on-the-fly and flexible add-ons for temperature control and dynamic clamp make this instrument the most versatile APC system on the market.