ResourceLife Sciences
Rapidly assess drug response in 2D and 3D breast cancer model systems with a luminescent viability assay
4 Mar 2024In recent years, the culture of cancer cells, along with other cell types, in three-dimensional (3D) formats where they can form multi-layered structures is enabling new models for cancer research that are considered more biologically relevant. In this application note from Molecular Devices, explore a small-scale study of cell viability in 2D and 3D cell cultures, measured using the CellTiter-Glo® 3D Cell Viability assay (Promega). Discover how Molecular Devices assayed the viability of two cell types grown in 2D and 3D and challenged with several previously tested compounds.
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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Drug TestingIt is essential to test the efficacy and toxicity of drugs at every stage of their development to ensure that a pharmaceutical product is fit for purpose and safe for use before reaching the stage of mass production and distribution.
