ResourceSpectroscopy
Quantitative Analysis of Human Tear Fluid by MALDI-TOF Mass Spectrometry
31 Jan 2019New sample clean-up methods for human tear uid were evaluated for a MALDI-TOF MS-based biomarker investigation approach. Additionally, a unique MALDI matrix was used to ionize hydrophobic peptides and proteins in tear.
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MALDI-8020 Benchtop MALDI-TOF Mass Spectrometer
Shimadzu CorporationProviding a dependable, robust, and easy-to-maintain platform, Shimadzu’s benchtop MALDI-8020 delivers sensitive detection and accurate mass determination by MALDI-TOF MS for a variety of analytes.
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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.
MALDI-TOF MSMALDI-TOF mass spectrometers (matrix-assisted laser desorption/ionization time-of-flight) are used for the mass analysis of large molecules, including proteins, DNA, polymers and other macromolecules due to its relatively soft ionization, reducing fragmentation whilst allowing fast data acquisition. Tandem mass analyzers such as TOF/TOF systems can be used to increase resolution and sensitivity of your analysis. Find the best MALDI-TOF products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Biomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.