ResourceClinical Diagnostics
PrimeStore molecular transport medium
6 Sept 2024The SARS-CoV-2 pandemic highlighted the limitations of modern molecular diagnostics testing, with safe sample collection being a major obstacle to address. Almost immediately after collection, the important nucleic acids in clinical specimens begin to degrade as they are exposed to nucleases and changes in temperature and pH. This can be an issue when these nucleic acids are used to make a diagnosis. Explore PrimeStore® MTM (molecular transport media) from Streck, a transport medium which is designed to rapidly inactivate viruses, bacteria, and veterinary pathogens at point-of-collection and stabilize DNA and RNA during storage and shipping.
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Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.Molecular DiagnosticsMolecular diagnostics use an individual’s genetic code and gene expression to diagnose and monitor diseases. The technique is used increasingly in the field of infectious diseases and oncology, as well as areas such as coagulation, HLA typing and pharmacogenomics. Molecular diagnostics plays a pivotal role in personalized medicine.