SPEAR UltraDetect Neurofilament light exceptional precision with F.A.S.T. automated workflow

20 Jan 2026

This application note focuses on SPEAR technology and its enhanced protein detection sensitivity and specificity compared to conventional immunoassays for detecting Neurofilament light in sub-microliter samples of serum or plasma. Integrated with the Formulatrix F.A.S.T. system, the wash-free assay workflow is further streamlined, reducing hands-on time to under 20 minutes and achieving remarkable precision (mean CV of 3.1%).

SPEAR UltraDetect™ NF-L Biomarker Assay Kit

Spear Bio

The SPEAR UltraDetect™ NF-L Biomarker Assay Kit lets you quantify neurofilament light with ultra-high precision, low sample volume, and a simple, wash-free workflow. Requires SPEAR UltraDetect™ Reaction Kit. For research use only.

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BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :qPCRQuantitative PCR (qPCR) is a molecular biology technique used to amplify and measure the amount of a specific DNA or RNA target. It plays a crucial role in gene expression analysis, pathogen detection, and quantifying DNA or RNA in various applications. Real-time PCR provides precise, quantitative results and is widely used in research, diagnostics, and clinical studies. Browse our peer-reviewed product directory to find the best qPCR solutions; compare products, check reviews, and get pricing directly from manufacturers.ImmunoassayImmunoassays are laboratory tests that utilize antibody-antigen interactions to detect specific substances. They are widely used in diagnostics for detecting diseases, drug testing, and environmental monitoring. These assays offer rapid, sensitive, and precise detection of biomarkers, making them invaluable in clinical and research labs. Browse our peer-reviewed product directory to compare immunoassay systems, read user reviews, and get pricing directly from manufacturers.NeurodegenerationNeurodegeneration refers to the progressive deterioration of the structure and function of the nervous system, often seen in diseases like Alzheimer's and Parkinson's. Research focuses on early detection and potential therapies. Explore neurodegeneration research tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.
SPEAR high-throughput automated assay for Neurofilament light using Formulatrix F.A.S.T.