ResourceSpectroscopy
Octet® Platform: A Complete Solution for Lot Release and In-process Testing of Biologics in GxP Laboratories
3 May 2018In this white paper, learn how Octet instruments by Pall ForteBio utilize Bio-Layer Interferometry technology to monitor biomolecular interactions in real-time. This can be used to quantify antibodies and recombinant proteins in a way that offers distinct advantages over ELISA and HPLC, including higher throughput and sample flexibility. BLI based assays are particularly suitable for various applications im GLPand QC laboratories including product potency testing and lot release.
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Octet® R8 BLI System
Sartorius GroupSuperior quantitation and kinetics performance with increased assay flexibility and cost efficiency.
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InterferometryInterferometry is an investigative technique used to analyze the pattern of interference created during the superposition of 2 or more waves. An interferometer is used to produce 2 or more overlapping waves. The interferometer is comprised of 2 or more telescopes, a detector and a correlator. The interferometer detector may utilize homodyne or heterodyne detection of the interference pattern.BiosensorsBiosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.Protein InteractionsProtein interactions are essential for understanding cellular processes, as proteins work together to carry out biological functions. Studying protein interactions can provide insights into disease mechanisms, drug development, and cell signaling pathways. Explore the best tools for protein interaction research in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Protein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.