ResourceLife Sciences
Multi-Parametric Assessment of Cell Phenotypes
23 Feb 2019Automated cellular imaging is an efficient method for analyzing compound effects on cell phenotypes including morphology, viability, and marker expression. Here, we demonstrate how the ImageXpress® Pico Automated Cell Imaging System and CellReporterXpress Automated Imaging and Analysis Software is applied for phenotypic analysis of compound effects. Imaging and analysis methods provide tools for characterization of multiple readouts including the assessment of cell viability, characterization of cell shape, cell adhesion and spreading, cytoskeleton integrity, and mitochondria potential.
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ImageXpress Pico Automated Cell Imaging System
Molecular Devices®Affordable cellular imaging and analysis system for individual biology labs - go from sample to results in minutes
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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.Cell ImagingCell imaging can be achieved using a number of techniques including confocal microscopy, transmission electron microscopy, atomic force microscopy, and light sheet microscopy.Phenotypic ScreeningPhenotypic screening assesses cellular responses to compounds, enabling drug discovery and target identification. This technique is pivotal in finding effective treatments for complex diseases. Discover phenotypic screening platforms and tools with peer-reviewed comparisons and pricing in our directory.