ResourceSeparations
Moving Your Old GC Methods to LC-MS/MS Technology to Enhance and Accelerate Environmental and Food Testing
8 Jun 2014This application note highlights benefits of advanced LC- MS/MS technology over GC for the analysis of environmental and food contaminants, which include:
- Less time-consuming and labor-intensive sample preparation
- Direct injection of water samples
- Typically no need for derivatization
- Short chromatographic run times
- Quantitation of trace levels (parts per trillion) due to superior selectivity and sensitivity of multiple reaction monitoring (MRM)
- Screening for a wider range of compounds in a single analysis
- Compound identification using MRM ratio calculation and library searching of enhanced product ion spectra
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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Food FraudFood adulteration refers to food when it has been has been altered unlawfully with the addition of another lower commodity food product to increase quantity. The 2013 European horsemeat scandal saw the adulteration of beef products with the addition of horse meat.Food TestingFood testing refers to a variety experiments including PCR, mass spectrometry, processing, QuEChERS, analyzing and Kjeldahl.