Integrated uHTS MALDI Sample Preparation and Mass Spectrometry with Analytik Jena and Bruker’s timsTOF MALDI PharmaPulse

9 Aug 2024

Discover the collaboration between Analytik Jena and Bruker, bringing you a cutting-edge liquid handling automation solution tailored for drug discovery screening. This innovative system integrates Bruker's MS System timsTOF MALDI PharmaPulse® with Analytik Jena's automated ultra-high throughput screening (uHTS) MALDI sample preparation. It provides a seamless combination of label-free mass spectrometry detection and high-efficiency sample processing.

timsTOF MALDI PharmaPulse

Bruker Daltonics

Gain new insights into molecular interactions and accelerate drug discovery with timsTOF MALDI PharmaPulse ® - the innovative technology for high-resolution label-free HTS.

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CyBio QuadStack

Analytik Jena GmbH+Co. KG

CyBio QuadStack is the high capacity bench top solution for microplate storage and with four stacker chimneys, the CyBio QuadStack offers the most tight and compact setup with a capacity of up to 260 plates. With different access modules the CyBio QuadStack provides you with the ultimate flexibility and speed. The CyBio Composer software guarantees easy system control. The CyBio QuadStack is the perfect combination for: CyBio Well CyBio Well vario Print and apply system Integrated robotic systems

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CyBio Well Vario

Analytik Jena GmbH+Co. KG

The CyBio Well Vario is CyBio´s automated, simultaneous pipetting platform which can be equipped with 11 interchangeable pipetting heads to offer highest pipetting precision and flexibility in a compact design. A large variety of disposable tips, highly precise ceramic tips or glass capillaries allow liquid transfers in a broad volume range of 4 orders of magnitude (25 nl up to 250 µl) on one pipetting system. 14 different capillary magazines are available for CyBio´s Capillary Head, which is especially designed for precise low-volume compound transfers (25—1000 nl). The CyBio Well vario is compatible with many specific accessories and can be adapted to every screening environment to create powerful liquid handling platforms for today and tomorrow. Optional stacker or dispenser integration together with the involvement of versatile peripheral devices can be easily implemented. Challenging liquid handling applications like working in high density microplate formats or in HTS environments can be easily achieved. CyBio´s outstanding customer service and application support is a well appreciated inherent part of every CyBio Well vario system. CyBio Well Vario Features: Extremely flexible through enormous volume spectrum Highest precision in the whole volume range Unique pipetting technology prevents cross contamination Easy application set-up using CyBio Composer software Saves reagent costs with accurate low volume pipetting

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Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.
Integrated uHTS MALDI Sample Preparation and Mass Spectrometry with Analytik Jena and Bruker’s timsTOF MALDI PharmaPulse