ResourceLife Sciences
Influence of heating rates on the thermostability characterization of antibodies by DLS and SLS
21 Jul 2022In this application note, the DynaPro® NanoStar® was used to study the impact of ramp rate on the apparent thermostability of trastuzumab (Her-ceptin), a commercially available mAb applied in the treatment of breast cancer. This study examined the effects of heating rate on the measured value of Tonset.
Related products
Request Quote for All Products
DynaPro™ NanoStar™ II Dynamic Light Scattering Detector
Waters | Wyatt TechnologyThe DynaPro™ NanoStar™ II DLS instrument determines size and molar mass with as little as 2 µL of solution.
Links
Tags
AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Dynamic Light ScatteringDynamic light scattering is used to measure the size distribution of particles in suspension by analyzing the way light scatters off them. It is commonly used in materials science, nanotechnology, and protein characterization. Browse our peer-reviewed product directory to find the best dynamic light scattering systems, compare products, check reviews, and get pricing directly from manufacturers.