ResourceClinical Diagnostics
Incucyte ATP Assay enables direct, live-cell measurement of ATP
28 Apr 2021Metabolically-targeted treatments are the subject of intense investigation in the oncology field. There is a critical need for improved tools to advance our understanding of how nutrient exchange and other cell-cell interactions influence the efficacy of potential therapeutic strategies.
In this application note, Sartorius describe the development and utility of the Incucyte® ATP Assay, encompassing novel reagents and purpose-built instrumentation and analytical tools with these needs in mind.
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Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.ATP MonitoringAssay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.