ResourceClinical Diagnostics
Humanized mouse models: Robust platforms for immuno-oncology & immunomodulation
15 Mar 2021In this application note, The Jackson Laboratory outlines the model comparison guide for study ready, humanized NSG™ mice which represent an innovative platform to evaluate human specific in vivo immune modulation, evaluation of drugs alone or in combination, and produce predictive data.
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ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Animal ModelsThe use of non-human animals in experiments or behavorial observations. The research is conducted inside universities, medical schools, pharmaceutical companies, farms, defence establishments, and commercial facilities that provide animal-testing services to industry. It includes pure research such as genetics, developmental biology, behavioral studies, as well as applied research such as pharmaceutical testing in pre-clinical, before human, studies.