How spatial phenotyping can uncover novel insights in tissue biology

8 Oct 2023

Spatial phenotyping allows a researcher to view, characterize, and quantify cells by lineage and variant with single-cell resolution in the context of an intact tissue sample. In areas such as oncology, immunology, and neurodegenerative disease it has opened new insights into the interplay between different cellular actors in promoting or suppressing disease. In this whitepaper from Akoya Biosciences, explore how to employ spatial phenotyping in your labs, and learn more about three examples of how it can impact your research tool kit.

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ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.ImmunophenotypingPhenotypic ScreeningPhenotypic screening assesses cellular responses to compounds, enabling drug discovery and target identification. This technique is pivotal in finding effective treatments for complex diseases. Discover phenotypic screening platforms and tools with peer-reviewed comparisons and pricing in our directory.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.
How spatial phenotyping can uncover novel insights in tissue biology