ResourceSeparations
High-purity Purification Method for Eicosapentaenoic Acid Ethyl Ester (EPA-EE) using a Newly Developed Reversed Phase Packing Material
High-purity Purification Method for Eicosapentaenoic Acid Ethyl Ester (EPA-EE) using a Newly Developed Reversed Phase Packing Material
5 Feb 2016Polyunsaturated fatty acids (PUFAs) including eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) are known to have anti-atherogenic and anti-hyperlipidimic effects. Recently, the market of PUFAs has expanded rapidly, especially the demand for high purity EPA ethyl ester (EPA-EE; > 95%) as an active pharmaceutical ingredient. This poster describes a novel reversed phase packing material and the method development for purification of EPA-EE using YMC-Omega.
Links
Tags
UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.PurificationPurification techniques are essential for isolating compounds of interest from complex mixtures, such as proteins, nucleic acids, and chemicals. These techniques are critical in biochemistry, drug development, and environmental studies. Explore purification systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Fatty AcidsReversed-Phase LC