ResourceDrug Discovery & Development
High concentration liposome and micelle suspension measurement
29 May 2023In this application note from Microtrac MRB, learn more about liposomes and micelles with particular attention to particle size measurement of liposomes in either dilute or concentrated aqueous environments. Furthermore, explore how liposomes are of special interest to the pharmaceutical industry in the development of drugs for targeting and delivery.
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Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.Particle CharacterizationParticle characterization instruments are used to determine particle size distribution, shape, surface area, zeta potential, density and porosity of particles and materials. Multiple tecchniques are available for determining particle size, shape and count including dynamic light scattering (DLS), laser diffraction, electrozone (Coulter technique), imaging particle analysis and single particle optical sensing. Determine the density of your material with a gas pycnometer or examine its surface area and porosity with gas adsorption analyzers and mercury porosimeters. Find the best particle characterization instruments in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Drug DevelopmentDrug development refers to the process of bringing a new drug to market.