Evaluation of Control Containing Ten Analytes for the Quality Assessment of Specialized Clinical Immunoassays

10 Mar 2014

Multi-analyte control material containing procalcitonin, 25 hydroxy vitamin D, 1-25 hydroxy vitamin D, osteocalcin, parathyroid hormone, C-peptide, insulin, anti-thyroglobulin and anti-thyroid peroxidase antibodies, and insulin-like growth factor, can be used in a variety of clinical fields. This study reports on the evaluation of a developed human multi-analyte control material, which can be used for the quality control of an expanded scope of specialized clinical immunoassays.

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HematologyIn Haematology / Hematology, complete blood cell counts (or full blood counts) are obtained using automated blood count analyzers to enumerate blood cell types.  Hematology also encompasses haemostasis and coagulation, thrombophilia and hemophilia, plasma viscosity and ESR analysis, hemoglobinopathies, cell morphology and haematinic measurement.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Point-of-CarePoint-of-Care Testing (POCT) or Near Patient Testing (NPT) products are available for urine, blood and other clinical chemistry analyses. POCT includes: blood glucose testing, blood gas and electrolytes analysis, rapid coagulation testing (PT / INR), rapid cardiac markers diagnostics, drugs of abuse screening, urine strips testing, pregnancy testing, fecal occult blood analysis, food pathogens screening, hemoglobin diagnostics, infectious disease testing and cholesterol screening.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.
Evaluation of Control Containing Ten Analytes for the Quality Assessment of Specialized Clinical Immunoassays