Evaluation of a Direct HbA1c Assay on a Fully Automated Chemistry Analyzer Versus Two Common HPLC Methods

19 Aug 2014

Pointe Scientific has developed a latex-enhanced immunotubidimetric assay that directly measures the percentage of HbA1c in whole blood. This study details an evaluation of the performance of this direct HbA1c assay on the Hitachi 917 chemistry analyzer, in comparison to a Tosoh G8 and a Bio-Rad Variant II (HPLC methods) at a large commercial lab.

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HematologyIn Haematology / Hematology, complete blood cell counts (or full blood counts) are obtained using automated blood count analyzers to enumerate blood cell types.  Hematology also encompasses haemostasis and coagulation, thrombophilia and hemophilia, plasma viscosity and ESR analysis, hemoglobinopathies, cell morphology and haematinic measurement.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.HBA1C
Evaluation of a Direct HbA1c Assay on a Fully Automated Chemistry Analyzer Versus Two Common HPLC Methods