Evaluating future Alzheimer’s disease p-Tau 181 and ApoE4 immunoassays for amyloid detection

15 Nov 2024

Full poster title: Revamping Alzheimer's disease diagnostics: Evaluating future IVD plasma p-Tau 181 and ApoE4 immunoassays for amyloid detection in a multi-center study reflective of routine clinical practice.

Early detection of amyloid pathology is a critical step in the Alzheimer's disease patient journey. Blood-based biomarkers have emerged as powerful tools in accurately identifying individuals' amyloid pathology. This poster shares findings from a study that investigated the clinical performance of plasma tau phosphorylated at threonine 181 (pTau181) in combination with plasma apolipoprotein E4 (ApoE4) as a potential diagnostic test to detect amyloid pathology.

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Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Alzheimers Disease
Evaluating future Alzheimer’s disease immunoassays p-Tau 181 and ApoE4 for amyloid detection