ResourceDrug Discovery & Development
Enhanced cell viability in multi-day microplate assays
3 Sept 2025This application note from Molecular Devices demonstrates how integrating the SpectraMax® aer Gas Mixer with SpectraMax® iD5e or iD3s Multi-Mode Microplate Readers significantly improves cell viability in multi-day assays. By mimicking incubator-like conditions the system supports healthier cell cultures over 72 hours. Using U-2 OS cells and luminescent viability assays (RealTime-Glo™ and CellTiter-Glo®), the study shows that gas-controlled environments yield results comparable to standard incubators and outperform ambient CO₂ setups. The solution is ideal for researchers conducting long-term live-cell assays requiring consistent environmental control.
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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell IncubationCell incubation involves maintaining controlled environmental conditions for growing and nurturing cells. It is essential for cell culture studies, drug testing, and regenerative medicine. Explore cell incubation solutions in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.