Dissolved oxygen control proportional–integral–derivative (PID) tuning for cell culture applications

26 Sept 2022

This application note introduces a method developed to optimize the PI values on Eppendorf bioprocess controllers. The method is based on pre-programmed delivery of chemical oxygen scavengers to accurately simulate the oxygen demand throughout a bioreactor cell culture process. This chemical simulation allows for quick and accurate tuning of PI values for cell culture dissolved oxygen control.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Oxygen Testing
Dissolved oxygen control proportional–integral–derivative (PID) tuning for cell culture applications