Eppendorf BioFlo® 320
The BioFlo 320 seamlessly blends beauty and utility in one all-inclusive package. A new industrial design, flexibility between interchangeable autoclavable and single-use vessels, intelligent sensors, Ethernet connectivity, and a new software package are only a few of the features that set it apart from the competition
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The BioFlo 320 seamlessly blends beauty and utility in one all-inclusive package. A new industrial design, flexibility between interchangeable autoclavable and single-use vessels, intelligent sensors, Ethernet connectivity, and a new software package are only a few of the features that set it apart from the competition.
Extensive options give you the customizable solution your lab requires. Combined with the strict quality standards that all Eppendorf products are held to, the BioFlo 320 truly is the new premium choice in benchtop bioprocess systems.
Features:
- Interchangeable autoclavable and BioBLU® single-use vessels
- Integrated Mettler Toledo Intelligent Sensor Management (ISM) platform
- Control up to eight (8) systems from a single-user interface
- Universal control for both microbial and cell culture applications
- Field-upgradable TMFC drawers for sparge and overlay gas
- Enhanced software package with new cascade and time profile features
- Built-in optical pH sensing technology for use with the BioBLU® single-use vessels
- Ethernet communication for multi-unit control, Eppendorf SCADA software, and IP addressing
- Up to six (6) integrated pumps capable of operating in variable speed mode
- Eight (8) independently controlled process gas supplies
Applications:
- Research and Development in cell culture and microbiology
- Laboratory and pilot scale fermentation of aerobic and anaerobic bacteria, yeasts and fungi
- Cultivation of mammalian, insect, and human cell lines
- Specialized applications such as stem cell culture or biofuel/biopolymer development
- Specialized packed-bed impeller for vaccine production in anchorage and non-anchorage dependent cell lines
- Suitable for batch, fed batch, and continuous processes
- Validation packages available for GMP regulated processes
From shaker to fermenter, a methanol-free Pichia pastoris protein production workflow
Pichia pastoris is widely employed for producing recombinant proteins. Traditional systems depend on methanol-inducible promoters like PAOX1, which pose safety concerns due to methanol’s flammable nature.
Find out more about a new strain of P. pastoris that carries a glycerol-inducible promoter, pUPP, that enables safe, methanol-free expression of proteins under glycerol feeding for high‑density fed‑batch fermentation.
Developing a highly robust, efficient, and cost-effective monoclonal antibody workflow
Since the COVID-19 pandemic, pressure has increased to develop more products for treating unexpected viral diseases at reduced costs, under safe conditions and in a timely manner. Monoclonal antibodies (mAbs) may hold great promise to fill this gap as an addition to vaccines and anti-viral drugs. Eppendorf has curated a mAb workflow to increase reproducibility and productivity of mAb research and development process. Explore how you can optimize process development, scale up, and device management to maximize yields and prevent instrument downtime.
Beginner's guide to CHO culture: Understanding batch, fed-batch, and perfusion bioprocesses
In this application note, Eppendorf explains the differences between batch, fed-batch, and perfusion cell culture bioprocesses using Chinese Hamster Ovary (CHO) cells at bench scale. The importance of tracking specific parameters is explained to achieve inoculation of bioreactors at high viability. The data obtained from sampling is discussed in terms of growth rate, production yields, and bioreactor feeding or perfusion rates. These principles may be applicable to other suspension cell culture processes at smaller or larger scales.
