Development of a Liquid Multi-Analyte Control Containing 100 Analytes to Increase Efficiency of the Analytical Performance Assessment

10 Mar 2014

The consolidation of quality control provided by liquid multi-analyte control material would be further enhanced by covering not only chemistry but also immunoassay and cardiac parameters, lipids, proteins, drugs, electrophoresis, trace metals. This study reports the development of a third party, liquid multi-analyte clinical chemistry control, containing 100 analytes (covering not only routine clinical chemistry but also other parameters) at clinically relevant levels, including CRP, C3, C4, ferritin, immunoglobins, transferrin.

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HematologyIn Haematology / Hematology, complete blood cell counts (or full blood counts) are obtained using automated blood count analyzers to enumerate blood cell types.  Hematology also encompasses haemostasis and coagulation, thrombophilia and hemophilia, plasma viscosity and ESR analysis, hemoglobinopathies, cell morphology and haematinic measurement.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Point-of-CarePoint-of-Care Testing (POCT) or Near Patient Testing (NPT) products are available for urine, blood and other clinical chemistry analyses. POCT includes: blood glucose testing, blood gas and electrolytes analysis, rapid coagulation testing (PT / INR), rapid cardiac markers diagnostics, drugs of abuse screening, urine strips testing, pregnancy testing, fecal occult blood analysis, food pathogens screening, hemoglobin diagnostics, infectious disease testing and cholesterol screening.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Clinical QC
Development of a Liquid Multi-Analyte Control Containing 100 Analytes to Increase Efficiency of the Analytical Performance Assessment