ResourceClinical Diagnostics
Determination of Arsenic Species in Urine Samples Using the PlasmaQuant® MS Elite
17 Oct 2017Arsenic toxicity, mobility and bioavailability can differ greatly between the various chemical species in which it exists. As a result, the reporting of total arsenic concentration only can often be misleading. This application note demonstrates a method for fast and accurate determination of arsenic species in urine, using the PlasmaQuant® MS Elite.
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Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.ICP-MSInductively Coupled Plasma Mass Spectrometry (ICP-MS) is a powerful analytical technique used to determine the concentrations of elements and their isotopes in a variety of samples, including water, soil, and biological tissues. It involves ionizing elements in the samples with extremely high-temperature Argon (Ar) plasma and then using a mass spectrometer to measure the number of ions based on their mass-to-charge ratio (m/z). Explore ICP-MS systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Molecular DiagnosticsMolecular diagnostics use an individual’s genetic code and gene expression to diagnose and monitor diseases. The technique is used increasingly in the field of infectious diseases and oncology, as well as areas such as coagulation, HLA typing and pharmacogenomics. Molecular diagnostics plays a pivotal role in personalized medicine.ArsenicArsenic is a toxic element that is used in the production of pesticides. Arsenic contamination of groundwater is a major issue for both drinking water and for uptake in foodstuffs such as rice.Clinical Mass SpectrometryMass spectrometry is emerging as a superior method of analysis over the longstanding, gold standard of immunoassay. Clinical mass spectrometry systems are increasingly accessible to medical laboratories and are capable of providing results with more speed and less expense than traditional methods. From simple mass spectrometers to IVDR class A compliant, highly sophisticated systems performing liquid chromatography tandem mass spectrometry (LC/MS/MS), find the latest product news, reviews and resources to make a purchasing decision for your laboratory. UrineThe analysis of urine is important in medicinal, anti-doping, forensic and life sciences applications. The ability to evaluate what someone has ingested through their urine enables fast detection and diagnosis of certain illnesses.