CRISPR Overview: Applying label-free insights to decipher CRISPR/Cas mechanisms and workflows

16 Jun 2020

In this application note, ForteBio provides examples of how Octet platforms were used not only to decipher CRISPR/Cas related interactions, but also to quantitate and validate downstream genetic manipulations mediated by the CRISPR/Cas machinery.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.DNADeoxyribonucleic Acid (DNA) is the main component of chromosomes and the carrier of genetic information of living organisms. Find out here about PCR, NGS, ChIP-Seq, gel imaging, and many other techniques which can be used for the analysis of DNA.CRISPRCRISPR technology enables precise editing of genes, allowing scientists to modify DNA at specific locations. This revolutionary tool is used in genetic research, drug development, and gene therapy. CRISPR has applications in agriculture, disease treatment, and creating genetically modified organisms (GMOs). Explore CRISPR solutions in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.
CRISPR Overview: Applying label-free insights to decipher CRISPR/Cas mechanisms and workflows