Controlled Release Diclofenac for Early Morning Pain and Stiffness
12 May 2014This poster describes the in vitro and in vivo analysis of a novel pulsatile release tablet system. The formulation provides an immediate release of diclofenac, followed by a delay consistent with typical sleep times, before pulsatile release of a second dose of the drug.
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Drug DeliveryDrug Delivery refers to dosage form, route of administration, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect. Drug delivery is often approached via the biopharmaceutical or small molecule drug's formulation, but it may also involve medical devices or drug-device combination products. Considerations include instrumentation, software and services. Drug DosageDosage is the size or frequency of the administration of a drug. Determination of the dosage of a drug is critical in pharmaceutical development to ensure the optimum balance between efficacy and toxicity.