ResourceLife Sciences
CLARIOstar Plus Simplifies Enzymatic Reaction Monitoring with its Novel Enhanced Dynamic Range Technology
22 Feb 2019Here, the detection of a β-gal enzyme assay that is primarily used for reporter assays was demonstrated. With the help of the EDR technology of the CLARIOstar Plus, β-gal mediated production of fluorescein was conveniently monitored. It allowed the detection of huge signal differences covering a range from 660 RFU up to 3.44*108 RFU. Translated to a reporter assay, this means very high and very low expressions can be measured at the very same plate. The tool simplifies the set-up of enzymatic assays as it does not require time to think about the right gain settings or repeat the assay until optimal settings are found.
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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.EnzymesEnzymes are macromolecular biological catalysts used across life science, pharmaceutical and clinical research. Various enzymes can be purchased for research applications including ligases, high fidelity polymerases, nuclease, protease, restriction enzymes, tissue dissociation enzymes and enzyme inhibitors. Find the best enzymes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.FluorescenceThe emission of fluorescence occurs when a photon of energy is supplied to a fluorescent chemical compound by an external source, causing it to become excited. Fluorescence can be detected and measured for different purposes using microplate readers, fluorescence microscopes, fluorescence scanners, and flow cytometers.Cell Based AssaysCell-based assays use living cells to measure biological responses to various treatments or stimuli. They are essential for drug discovery, toxicology testing, and understanding cellular mechanisms. These assays are used to assess cell viability, proliferation, gene expression, and other cellular activities. Browse our peer-reviewed product directory to find the best cell-based assay tools and reagents, compare products, read customer reviews, and get pricing directly from manufacturers.
