ResourceDrug Discovery & Development
Bridging the gap in PROTAC development
18 Sept 2025Targeted protein degradation is redefining drug discovery by offering a way to eliminate disease-causing proteins once considered 'undruggable'. By hijacking the cell’s natural ubiquitin-proteasome system (UPS), technologies like PROTACs and molecular glues enable selective degradation of proteins lacking traditional binding sites. Yet, challenges such as poor solubility, limited cell permeability, and off-target effects continue to hinder progress.
Discover how ChemPartner’s UPS Assay Platform addresses these barriers by interrogating 11 key steps, ensuring every step of the degradation pathway is investigated.
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Discovery SoftwareComputational techniques used in both the chemistry and biology aspects of drug discovery, for data acquisition, processing and storage. Software is used for analysis of pathways, target identification, genomics, proteomics, modelling, lead identification, compound analysis and drug modelling among many others. ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.OncologyThe branch of medical science that deals with the diagnosis and treatment of cancer is known as oncology.NeurologyInflammatory Diseases