Automated organoid workflow for T-cell screening assay using the CellXpress.ai System

13 Oct 2025

Explore an automated, dome-free workflow for T-cell screening using patient-derived colorectal cancer organoids and the CellXpress.ai® Automated Cell Culture System. This poster showcases how the system streamlines organoid seeding, T-cell co-culture, and high-content imaging—enabling precise, high-throughput analysis of T-cell penetration behavior in a 3D tumor-like environment. The workflow leverages IN Carta® Image Analysis Software to quantify chemotactic responses to varying PMA concentrations, offering a powerful model for evaluating immunotherapeutic efficacy.

CellXpress.ai Automated Cell Culture System

Molecular Devices®

The CellXpress.ai™ Automated Cell Culture System is an AI-driven cell culture innovation hub that gives your team total control over demanding cell culture feeding and passaging schedules—eliminating time in the lab while maintaining a 24/7 schedule for growing and scaling multiple stem cell lines, spheroids, or organoids.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.OrganoidsT Cells
Automated organoid workflow for T-cell screening assay