Application of Desorption Electrospray Ionization (DESI) for Breast Tissue Imaging in Clinical Research

16 May 2017

The goal of this study was the introduction of the desorption electrospray ionization technique coupled to mass spectrometry imaging using a Xevo® G2-XS Quadrupole Time-of-flight Mass Spectrometer for distinguishing tissue types in breast samples for clinical research.

SYNAPT G2-Si MS

Waters

Transform your lab's discovery capability with the SYNAPT G2-Si MS. Information. Informatics. Impact. SYNAPT enables extensive characterization of complex mixtures and molecules with uncompromising qualitative and quantitative performance, streamlined workflows and unparalleled platform versatility. With the SYNAPT G2-Si you get ultimate UPLC/MS/MS performance, powerful data independent & data dependant solutions, CID and ETD fragmentation capabilities, and a wide range of experimental options.

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Xevo G2-XS QTof

Waters

Xevo G2-XS QTof - eXtreme Sensitivity, eXtraordinary Selectivity, eXceptional Solutions. For the scientist who needs to identify, quantify and confirm the broadest range of compounds in the most complex and challenging samples the Xevo G2-XS QTof provides maximum robustness with no compromise in performance, class-leading real-world quantitative sensitivity, the highest quality, most comprehensive qualitative information, flexibility to adapt to changing needs and is accessible to experts and non-experts alike.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. ImagingImaging techniques are essential for obtaining visual representations of samples to understand structures, processes, and function in biological, chemical, and physical research. These tools range from traditional light microscopy to advanced imaging modalities like MRI and electron microscopy, providing researchers with valuable data for diagnostics, drug discovery, and material analysis. Explore imaging solutions in our peer-reviewed product directory to compare products, check reviews, and get pricing directly from manufacturers.Electrospray Ionization
Application of Desorption Electrospray Ionization (DESI) for Breast Tissue Imaging in Clinical Research