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Addressing the analytical gaps in modern therapeutic development

Svar Life Science AB
1 Sept 2025

As biopharmaceuticals evolve toward complex modalities like gene therapies and immune-modulating biologics, traditional analytical methods often fall short. Cell-based assays are rising as essential tools but developing robust, context-specific solutions remains challenging.

Discover how tailored cell-based assay strategies can overcome these hurdles and support regulatory-ready data generation. Explore the key challenges and find practical guidance to help advance your analytical capabilities for next-generation therapeutic development.

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iLite® Custom Development & Cell-based Services

Svar Life Science AB

With their proprietary technology, the iLite® technology Svar can develop Report Gene Assays – that area cleverly designed, sensitive and specific cell based reporter-gene system with luciferase readout. Svar can develop assays for virtually any pharmaceutical target that allow an easy, rapid and accurate test format for a wide range of applications, such as Immunogenicity and Potency assays.

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iLite® Cell-based Complement Bioassays

Svar Life Science AB

Svar specializes in creating cell-based Reporter Gene Assays with iLite® technology for a range of complement applications. This technology offers a precise, sensitive system with luciferase readout, suitable for assessing drug activity for different targets such as C5a, and through Complement-Dependent Cytotoxicity (CDC) activity.

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iLite® Cell-based Solutions

Svar Life Science AB

Svar specializes in creating cell-based Reporter Gene Assays with iLite® technology for a range of applications. This technology offers a precise, sensitive system with luciferase readout, suitable for testing drug activity, immunogenicity, and Fc-functional assays including CDC, ADCC, and ADCP activity. Svar's development capabilities cover nearly any pharmaceutical target, ensuring rapid and accurate assays.

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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.CAR-T cell therapyCell Line DevelopmentBiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.

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