A method for preparing tumor tissues for ex vivo culture that retains T cells within live tumor fragments (LTFs) while preserving tissue viability and T cell function

19 Sept 2025

Traditional tissue preparation methods can disrupt the tumor microenvironment (TME), which poses challenges for characterizing responses to immunotherapy in live tumor fragments (LTFs).

In this scientific poster, Elephas Biosciences presents a method that incorporates automated cutting instruments designed to optimally fragment tumor resections and core needle biopsies (CNBs), and a proprietary hydrogel that supports the TME of LTFs in ex vivo culture.

Links

Tags

Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.TumorsTumor research focuses on understanding abnormal cell growth that leads to cancer. Identifying biomarkers, studying tumor microenvironments, and developing targeted therapies are critical for advancing cancer treatment. Early detection and personalized treatment options are key to improving outcomes for patients. Browse our peer-reviewed product directory to explore tools for tumor research, diagnostics, and cancer therapies; compare products, read customer reviews, and get pricing directly from manufacturers.Tissue ProcessingTissue processing involves preparing biological tissue samples for microscopic analysis, including fixation, embedding, and sectioning. This process is essential for histopathology and diagnostic applications. Explore tissue processing products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.
A method for preparing tumor tissues for ex vivo culture that retains T cells within live tumor fragments (LTFs) while preserving tissue viability and T cell function