ADME-Toxicology Products & Reviews

Annexin V Alexa Fluor 647 Ready Flow Conjugate is a bright, easy-to-use stain for apoptosis with high affinity for phosphatidylserine (PS), which becomes exposed on the outer leaflet of cells undergoing apoptosis. The Annexin V Alex Fluor 647 conjugate is excitable at 650 nm with an emission peak at 665 nm.FeaturesStable at room temperatureConvenient, ready-to-use format—no need to dilute, weigh, or pipetteCan be added directl…

Annexin V APC Ready Flow Conjugate is a bright, easy-to-use stain for apoptosis with high affinity for phosphatidylserine (PS), which becomes exposed on the outer leaflet of cells undergoing apoptosis. The Annexin V APC conjugate is excitable at 650 nm with an emission peak at 660 nm.FeaturesStable at room temperatureConvenient, ready-to-use format—no need to dilute, weigh, or pipetteCan be added directly to Ca2+-containing me…

Annexin V Pacific Blue Ready Flow Conjugate is a bright, easy-to-use stain for apoptosis with high affinity for phosphatidylserine (PS), which becomes exposed on the outer leaflet of cells undergoing apoptosis. The Annexin V Pacific Blue conjugate is excitable at 410 nm with an emission peak at 455 nm.FeaturesStable at room temperatureConvenient, ready-to-use format—no need to dilute, weigh, or pipetteCan be added directly to…

Detects apoptotic cells in situ by the indirect TUNEL method, utilizing an anti-digoxigenin antibody that's conjugated to a Fluorescein reporter molecule

Available in 25, 100 or 300 test packs. Annexin V (or Annexin A5) is a member of the annexin family of intracellular proteins that binds to phosphatidylserine (PS) in a calcium-dependent manner. PS is normally only found on the intracellular leaflet of the plasma membrane in healthy cells, but during early apoptosis, membrane asymmetry is lost and PS translocates to the external leaflet. Fluorochrome-labeled Annexin V can t…

ProQinase's CL100-ProliFiler is a standard service package comprising IC50 determination of your test compounds on the proliferation response of a defined panel of 100 tumor cell lines.

This assay kit provides an easy-to-use, non-radioactive, histological and FACS-based method for measuring cell proliferation, cell viability, chemotaxis, cytotoxicity and apoptosis. The kit provides a two-color fluorescence method that is based on the simultaneous determination of live and dead cells using two different dyes.  Live cells and intracellular esterase hydrolyzes the dye to produce a hydrophilic, strongly fluore…

Use the CFDA-SE (5[6]Carboxyfluorescein diacetate, succinimidyl ester) cell-permeable dye to monitor cell population health.

Commonly used in flow cytometry experiments for excluding dead cells, the propidium iodide solution enters a compromised cell and binds to double-stranded DNA/RNA by intercalating between base pairs.

The ReadiDrop™ 7-aminoactinomycin D (7-AAD) cell viability assay is designed as a ready-to-use 7-AAD solution, which binds double-stranded DNA with a high-affinity intercalation between GC base pairs.

CytoTrack cell proliferation assays are designed to efficiently stain live cells for excellent resolution of each cell division generation.

CytoTrack cell proliferation assays are designed to efficiently stain live cells for excellent resolution of each cell division generation.

CytoTrack cell proliferation assays are designed to efficiently stain live cells for excellent resolution of each cell division generation.

1 x 96-well, includes magnetic capture beads, detection antibodies, standards, controls, diluent, buffers, streptavidin-PE, flat bottom plate, and plate seals, for the detection of 6 human kidney toxicity markers in urine

1 x 96-well, includes magnetic capture beads, detection antibodies, standards, controls, diluent, buffers, streptavidin-PE, flat bottom plate, and plate seals, for the detection of 6 human kidney toxicity markers in urine

Get faster staining and more accurate results - without the need for wash steps or quencher dye

Allows sensitive colorimetric assays for the determination of cell viability in cell proliferation and cytotoxicity assays

CFSE Cell Division Tracker Kit is composed of 5 vials, 100 µg per vial of CFSE (formally known as 5-(and 6)-Carboxyfluorescein diacetate succinimidyl ester of CFDA SE), and 500 µl of anhydrous DMSO. CFSE is able to passively diffuse into cells. Inside the cell, its acetate groups are cleaved by intracellular esterases, and the molecules are converted to fluorescent esters. CFSE is retained within the cell and covalently couple…

Off-the-shelf cryopreserved human cells for generation of hepatic spheroids in your own lab

Pooled population of primary hepatocytes

Our HybridSPE ® -PLus plates effectively remove phospholipids and proteins from biological matrices in a simple pass-through method for accurate and reproducible LC-MS analysis. Unlike other phospholipid removal SPE products on the market, the unique retention mechanism of HybridSPE ® allows for separation of even very hydrophobic analytes from phospholipid contaminants.     

Quickly and accurately identify tricyclics in serum samples with Thermo Scientific™ DRI™ Tricyclics Serum Toxicology Assays, excellent tools for emergency rooms when urine specimens are not conveniently available.

Supel™ Swift HLB is a polymeric stationary phase for solid phase extraction (SPE) prior to instrumental analysis. It has both hydrophilic and lipophilic functional groups for the extraction of a broad range of compounds from aqueous samples. It retains analytes having diff erent polarities and Log P values due to its hydrophilic and lipophilic balance (HLB) property.

HistologiX is a leading GLP/GCP accredited Contract Research Organisation based in the UK specialising in Histology, Immunohistochemistry (IHC) and Digital Pathology services. HistologiX works with a broad range of clients from big pharma to small and medium biotech companies worldwide. Our team of scientists have in excess of 120 years combined experience and a customer retention rate of 80%. 

HistologiX is a leading GLP/GCP accredited Contract Research Organisation based in the UK specialising in Histology, Immunohistochemistry (IHC) and Digital Pathology services. HistologiX works with a broad range of clients from big pharma to small and medium biotech companies worldwide. Our team of scientists have in excess of 120 years combined experience and a customer retention rate of 80%.