Solid-Phase Extraction Products & Reviews

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Solid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Presto

PromoChrom Technologies

The Presto 8-Channel Accelerated SPE System, engineered for unparalleled efficiency, is the ultimate solution for handling large volumes or samples with high particulate matter.

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Biotage® VacMaster™ Manifolds

Biotage

Biotage® VacMaster™ Sample Processing Manifolds allow samples to be processed simultaneously under vacuum. Easy-to-use vacuum controls provide excellent sample flow control, leading to reproducible, reliable extraction conditions.

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ISOLUTE® PLD+ for PFAS Analysis in Biological Samples

Biotage

ISOLUTE® PLD+ for PFAS enables fast, simple “crash and filter” sample clean-up without conditioning or washing steps, delivering matrix-free extracts for accurate LC-MS/MS quantitation. Designed with low-background components, it ensures reliable PFAS recovery from complex biological samples.

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Quadra Liquid Handling Workstation

Hudson Lab Automation

The Quadra Liquid Handling Workstation automates complex workflows such as SPE, serial dilutions, and assay reformatting with unmatched precision and flexibility across various well plate formats. Its compact design, high-throughput capabilities, and seamless LIMS integration make it the perfect solution for labs seeking to enhance efficiency, scalability, and data traceability.

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InertSep Stacked SPE for PFAS

GL Sciences, Inc.

EPA Method 1633 efficiently determines PFAS in complex samples. InertSep, a line of solid-phase extraction cartridges, is known for high purity, consistency, and quality. InertSep WAX FF and GCB offer high recovery rates and cleanup efficiencies for PFAS in water, soil, food, and other complex matrices. InertSep GCB, packed with Graphite Carbon Black, is ideal for LC/MS analysis due to its excellent cleanup efficiency.

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EVOLUTE® PFAS Solid Phase Extraction Columns

Biotage

EVOLUTE® PFAS SPE columns deliver high, reproducible recoveries of PFAS analytes with high-purity WAX sorbent and low-background components to prevent contamination. Available in 50 µm and 30 µm formats for compliance with ISO and EPA 533 methods, they are ideal for both manual and automated workflows.

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InertSep QuEChERS Kit

GL Sciences, Inc.

InertSep QuEChERS Kit is a product developed by leveraging decades of expertise in manufacturing high-quality chromatography products. This kit efficiently removes impurities such as organic acids, sugars, fatty acids, pigments, chlorophyll, and carotenoids from samples, enhancing the accuracy and reliability of subsequent analyses using LC/MS or GC/MS.

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Centri 180

Markes International Ltd

Versatile platform for high-sensitivity routine analysis using headspace-, SPME-, thermal desorption- and HiSorb™ high-capacity sorptive extraction-based workflows

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Biotage® Extrahera™ Peptide

Biotage

Biotage® Extrahera™ Peptide automates sample workup with precision and ease. Designed for synthetic labs, it enables automated solid phase extraction (SPE) and catch-and-release purification of up to 96 samples simultaneously. Positive pressure processing and complementary consumables ensure consistent, high-purity peptide samples free of catalysts and excess reagents.

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EVOLUTE® SPE Columns and Plates

Biotage

EVOLUTE® Sample Preparation products feature advanced water-wettable polymer-based sorbents that deliver clean extracts and consistent analyte recovery for accurate LC-MS/MS quantification. Designed to minimize ion suppression and matrix effects, they provide reliable performance across a wide range of acidic, basic, and neutral compounds.

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InertSep Oligo

GL Sciences, Inc.

InertSep Oligo is a solid-phase extraction (SPE) product for oligonucleotide purification in LC/MS workflows. It delivers high recovery, low variability, and full LC/MS compatibility. Formats include 96-well plates—Micro Elution (2 mg/400 µL) and 2 mL square-well (25 mg)—and straight barrel cartridges in multiple sizes for manual or automated high-throughput sample prep.

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InertSep Micro Elution 96-well Plate

GL Sciences, Inc.

Meet the InertSep Micro Elution SPE Plate: elongated wells and a high-efficiency 2 mg sorbent bed drive strong retention with just 25–150 µL elution. Skip dry-down, use less solvent, and accelerate LC–MS/MS workflows. Handle 10–100 µL samples with excellent recovery across HLB, MCX/WCX, and MAX/WAX chemistries.

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SPE - Solid Phase Extraction Workstation

Xiril AG

The solid phase extraction (SPE) workstation can be used on Xiril pipetting workstations for automated nucleic acid purification based on vacuum technology. All pipetting steps of several different nucleic acid purification kits can be automated on a Xiril liquid handling workstation. Xiril’s very space saving SPE vacuum station comprises two positions, one in the front for washing steps and another in the back for the elution…

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miVac Concentrators

Genevac

miVac is a range of centrifugal vacuum concentrators and freeze driers capable of removing water and organic solvents from a variety of sample formats including tubes, microplates, and vials. miVac concentrators come in 2 sizes, the smaller Duo and a larger Quattro. There is a choice of vacuum pump and rotor according to application and sample format.  To speed concentration built-in special runs for working with water and…

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DisQuE Quechers, AOAC Method Sample Preparation Kit, Pouches

Waters

DisQuE Dispersive Sample Preparation used for QUECHERS Method AOAC Method 2007.01. The kit consists of 100 units each of salt pouches, empty 50mL centrifuge tubes and clean-up tubes. Each DisQuE pouch contains 6 grams of magnesium sulphate and 1.5 grams of sodium acetate. Each 2 mL DisQuE Clean-Up tube contains 150 mg of magnesium sulphate and 50 mg PSA (primary-secondary amine SPE sorbent)

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Solid Phase Extraction Products (SPE cartridges & Well Plates) – SiliaPrep™ & SiliaPrepX™

SiliCycle Inc.

Solid Phase Extraction (SPE) is the basis of analytical laboratories. A crucial step of this process is sample preparation. Therefore we know that a clean sample will yield better results. To achieve this goal SiliCycle has designed SiliaPrep, which is a silica based sorbent exempt of fines, and SiliaPrepX, polymeric based sorbent, that can be found in cartridges, well plates and SPME (Solid Phase Micro-Extraction) cartridges…

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QUECHERS – SiliaQuick™

SiliCycle Inc.

There is a growing need for applications in food and environmental areas able to cope with the analysis of a large number of analytes in very complex matrices. New analytical procedures demand sensitivity, robustness, effectiveness and high resolution with reduced analysis time. To improve the efficiency of traditional methods, a new sample preparation approach was developed. It’s called QuEChERS and it says it all: an acrony…

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