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HitKit® HCS Reagent Kit for c-Jun Activation

Phosphorylation of c-jun is measured by an increase in fluorescence in the nucleus of cells.  This kit includes antibodies, buffers, and a complete protocol for preparation of imaging-quality cells in microplates.  The secondary antibody is conjugated to Alexa® Fluor 488 for optimal detection of phospho-c-jun with a FITC emission filter.  The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be applied…

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HitKit® HCS Reagent Kit for ERK MAPK Activation

Activation of ERK can be detected by an increase in phospho-specific fluorescence in the nucleus of cells.  This kit includes antibodies, buffers, and a complete protocol for preparation of imaging-quality, fluorescently labeled cells in microplates.  The secondary antibody is conjugated to Alexa® Fluor 488 for optimal signal with a FITC emission filter.  The kit has been validated on Cellomics’ ArrayScan® HCS Reader but may b…

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HitKit® HCS Reagent Kit for Micronucleus

The Micronucleus reagent kit comprises three spectrally distinct fluorophores that label cellular targets to allow assessment of genotoxicity/ clastogenicity by looking at several biological parameters.  This kit contains fluorescent probes that label whole cells, nuclei, micronuclei, and permeabilized cells.  The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be applied to any imaging system.  Avai…

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HitKit® HCS Reagent Kit for Mitotic Index

The Mitotic Index Kit includes antibodies, buffers, and a complete protocol for preparation of imaging-quality, fluorescently labeled cells in microplates.  An antibody to phospho-histone H3 detects cells in early mitosis, and DNA content correlates with intensity of the nuclear-binding dye.  The secondary antibody contains Alexa® Fluor 488.  The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be app…

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HitKit® HCS Reagent Kit for Neurite Outgrowth

The Neurite Outgrowth Kit labels the neuronal form of tubulin to detect neurons and neurites, to enable assessment of neurite outgrowth.  This kit includes fluorescent antibodies, buffers, and a complete protocol for preparation of imaging-quality cells in microplates.   The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be applied to any imaging system. Available in Evaluation Size (Five 96-well pl…

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HitKit® HCS Reagent Kit for NFAT Activation

Translocation of NF-AT is measured by an increase in fluorescence in the nucleus of cells.  This kit includes antibodies, buffers, and a complete protocol for preparation of imaging-quality, fluorescently labeled cells in microplates.  The secondary antibody is conjugated to Alexa® Fluor 488 for optimal signal with a FITC emission filter.  The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be applie…

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HitKit® HCS Reagent Kit for NFkB Activation

Activation of NFkB can be detected by an increase in fluorescence in the nucleus of cells.  This kit includes antibodies, buffers, and a complete protocol for preparation of imaging-quality, fluorescently labeled cells in microplates.  The secondary antibody is conjugated to Alexa® Fluor 488 for optimal signal with a FITC emission filter.  The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be applie…

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HitKit® HCS Reagent Kit for p38 MAPK Activation

Activation of p38 MAP kinase is measured by an increase in fluorescence in the nucleus of celsl.  This kit includes antibodies, buffers, and a complete protocol for preparation of imaging-quality cells in microplates.  The secondary antibody is conjugated to Alexa® Fluor 488 for optimal detection of phospho-p38 with a FITC emission filter.  The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be appli…

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HitKit® HCS Reagent Kit for PKCa Activation

This reagent kit comprises three spectrally distinct fluorophores that allow assessment of cytoplasm-to-cell membrane translocation of PKC alpha.  This kit specifically labels nuclei (blue), cell membrane (Alexa Fluor(r) 488), and PKC alpha (Alexa Fluor 555) in mammalian cells.  The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be applied to any imaging system.  Available in Evaluation Size (Five 9…

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HitKit® HCS Reagent Kit for STAT1 Activation

Activation of STAT1can be detected by an increase in fluorescence in the nucleus of cells.  This kit includes antibodies, buffers, and a complete protocol for preparation of imaging-quality, fluorescently labeled cells in microplates.  The secondary antibody is conjugated to Alexa® Fluor 488 for optimal signal with a FITC emission filter.  The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be applie…

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HitKit® HCS Reagent Kit for STAT2 Activation

Translocation of STAT2 is measured by an increase in fluorescence in the nucleus of cells.  This kit includes antibodies, buffers, and a complete protocol for preparation of imaging-quality, fluorescently labeled cells in microplates.  The secondary antibody is conjugated to Alexa® Fluor 488 for optimal signal with a FITC emission filter.  The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be applie…

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HitKit® HCS Reagent Kit for STAT3 Activation

Activation of STAT3 is measured by an increase in fluorescence in the nucleus of cells.  This kit includes antibodies, buffers, and a complete protocol for preparation of imaging-quality, fluorescently labeled cells in microplates.  The secondary antibody is conjugated to Alexa® Fluor 488 for optimal signal with a FITC emission filter.  The kit has been validated on Cellomics’ ArrayScan® HCS Reader but may be used on any imagi…

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Neuroscreenâ„¢-1 Cells, Academic Package

Neuroscreen-1 is a neuronal-like cell line optimized for screening.  It is a subclone of PC12, a widely used cell line derived from rat pheochromocytoma cells that serves as a standard model system for neurons.  Neuroscreen-1 cells display several substantial advantages over PC12 cells, including 50-80% faster growth, no tendency toward cell aggregation, high and accelerated responsiveness to NGF (measurable neurites within 2…

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Neuroscreenâ„¢;-1 Cells, Commercial Package

Neuroscreen-1 is a neuronal-like cell line optimized for screening.  It is a subclone of PC12, a widely used cell line derived from rat pheochromocytoma cells that serves as a standard model system for neurons.  Neuroscreen-1 cells display several substantial advantages over PC12 cells, including 50-80% faster growth, no tendency toward cell aggregation, high and accelerated responsiveness to NGF (measurable neurites within 2…

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ProductsSeparations

RediSep® Alumina Columns

Teledyne Labs

Neutral alumina columns are useful when samples are acid sensitive and prone to degradation on normal phase silica gel. Acid and basic alumina columns are useful when purification of a compound with those properties is considered. This avoids the solvent swapping and additional extraction, washing, and concentration involved in recovering target compounds from collected fractions containing a mobile phase modifier such as tri…

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ProductsSpectroscopy

MIAS-2 Multimode Microscopy Reader

MAIA SCIENTIFIC

MIAS-2 readers are a new generation of HTS microscopy readers with an unequaled blend of sensitivity, flexibility and speed.  They are designed to cover the throughput and flexibility needs at multiple phases across the R&D value chain.  In drug discovery R&D, applications include target identification, target validation, assay development, high throughput screening, hit-to-lead, deep pharmacology and ADMET.  Unique features…

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eaZYX Image Analysis Software

MAIA SCIENTIFIC

eaZYX is a high-end and yet easy-to-use software platform for image acquisition, analysis that is composed of three parts: eaZYX-IMAGING, eaZYX-PROOFING and eaZYX-AUTOMATION.  eaZYX-IMAGING is the image analysis core software engineUnlike many image analysis softwares, eaZYX uses a holistic principle to ‘look’ at images.  It does not segment pixel information to pull forward certain features in the image using a ‘pixel-by-pixe…

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Corning® 500cm² Square TC-treated Culture Dish

Corning Life Sciences

(This is the suggested replacement for 431112) Approximate growth surface area is 500 cm² Actual internal growth surface dimensions is 224 x 224mm Height is 25mm Manufactured from optically-clear virgin polystyrene Treated for optimal cell attachment Sterile and nonpyrogenic Have stacking beads to aid in handling Supplied with vents to provide consistent gas exchange Design allows for easier handling Customer Revie…

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Supercritical Reactors/ Reaction Systems

Waters

Thar's SuperReactor/Extractor systems are built to enable the user to rapidly react multiple compounds with supercritical CO2, video record it occuring, then extract materials of interest. The user can operate in a static, pressure control mode or a dynamic flow control mode. No other company in the world produces off-the-shelf, automated SFR/SFE kits for use in pharmaceutical, chemical and food research laboratories. Superc…

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ProductsSeparations

High Pressure Pumps

Waters

Thar designs and manufactures high pressure pumps ideally for high pressure and high temperature applications, such as supercritical fluid chromatography (SFC), HPLC, supercritical fluid extraction (SFE), particle formation, reactions, solvent extractions. The pumps can be controlled using a hand-held display (included) or PC via the built-in RS232C interface. The high pressure pump can be used in conjunction with additional…

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