Products & Reviews

BRET-Based Assays to Detect Protein:Protein Interactions in Live Cells

Simple, Plate-Based Assay for Real-Time Apoptosis Detection

Efficient Lysis of E. coli Cultures; No Centrifugation or Mechanical Disruption Needed FastBreak™ Cell Lysis Reagent is provided as a 10X concentrate and contains a proprietary nonionic detergent to facilitate lysis. Add the reagent directly to E. coli cultures. Following a brief incubation, the cells are disrupted, and the protein  released. Recombinant proteins can be directly screened in the cell extract or purified by t…

Characterize MSI Status of Your Research Samples

A Complete Solution for Monitoring LC and MS Instrument Quality Control and Performance. In combination with an accompanying software tool, the 6 × 5 LC-MS/MS Peptide Reference Mix provides a convenient way to assess LC column performance and MS instrument parameters, including sensitivity and dynamic range. Consists of 30 peptides; 6 sets of 5 isotopologues of the same peptide sequence, differing only in the number o…

The small size and bright luminescence of NanoLuc® luciferase bring exquisite sensitivity to many applications. From NanoBRET™ technology, a BRET-based method to study protein:protein and protein:small molecule interactions, to NanoLuc® Binary Technology (NanoBiT), NanoLuc is the cornerstone for studying genetic responses and protein dynamics in cells at physiologically relevant levels. The flexibility of NanoLuc® technologies…

All-In-One Processing for Large-Volume Purification Chemistries

Full-Length cDNA Synthesis for the Analysis of Rare or Long Messages

Measure Chymotrypsin-, Trypsin- and Caspase-Like Activities

Superior Size Selection and Recovery for NGS and PCR

A Simple, Non-Radioactive Assay to Measure Glucose Uptake Inside Cells

Human Genomic DNA

Automated Extraction of DNA from Blood or Buffy Coat Samples

Reliable Transfection for Common Cell Lines

Single-Use Ligands for High-Resolution lmaging in Live Cells

Capped or Uncapped RNA Transcripts for in vitro or in vivo Translation

Digitonin can be used in cell viability and cytotoxicity assays. It is a detergent solution useful for permeabilizing cells and for creating a cytotoxicity chemistry positive control. Supplied at 20mg/ml in DMSO

Extract high-quality nucleic acids with less hands-on time.

Rapid detection of firefly luciferase activity with amazing sensitivity and dynamic range.

High-Throughput Extraction of DNA from FFPE Samples Robust, precipitation-free protocol, no chance of lost pellets High yields of pure DNA from FFPE samples without using xylene or other hazardous chemicals Ideal for use in downstream applications including qPCR and next-generation sequencing (NGS)

The SV 96 Total RNA Isolation System provides a high-throughput technique to prepare intact RNA from tissue and cultured cells. Total RNA can be purified from 96 samples in less than an hour without centrifugation. The system incorporates a DNase treatment step that is designed to substantially reduce genomic DNA contamination, which can interfere with amplification-based methodologies. Purification is achieved without phenol:…

Column-based method for rapid concentration and cleanup of DNA.

Column-based method for rapid concentration and cleanup of RNA.

LDH-Glo™ Cytotoxicity Assay detects cell death from a small number of cells, including 3D cell cultures, based on the release of lactate dehydrogenase.

The RealTime-Glo™ MT Cell Viabiilty Assay measures viability of cells in a non-lytic, real-time live-cell format, saving time, cells and reagent costs.