Enzymes Products & Reviews

cAMP pathway activator; Inhibits type 4 cyclic nucleotide phosphodiesterases (PDE4)

Epigenetic modifier; Inhibits HDAC1 and HDAC3

p38 MAPK inhibitor

p38 MAPK inhibitor

WNT pathway activator; Inhibits GSK3a and GSK3ß

Activin/BMP/TGF-ß pathway inhibitor; Inhibits ALK4, ALK5, and ALK7

NHEJ pathway inhibitor; inhibits DNA ligase IV

Epigenetic modifier; Inhibits DNA methyltransferases (DNMTs)

Epigenetic modifier; Inhibitor of Sir2p, SIRT1, and SIRT2

Activin/NODAL/TGF-ß pathway inhibitor; Inhibits SMAD3

JNK pathway inhibitor; Inhibits JNK1, JNK2 and JNK3

Epigenetic modifier; Inhibitor of Sir2p

JAK/STAT pathway inhibitor; Inhibits STAT5

Calcium signaling inhibitor; Inhibits calcium/calmodulin-dependent kinase kinases (CaMKKs)

HGF pathway inhibitor; Inhibits MET

MEK/ERK pathway inhibitor; Inhibits VEGFR2, FGFR1, and PDGFRB

Tyrosine kinase inhibitor; Inhibits of KDR, PDGFR, KIT, RET, FLT-3, ABL and ALK

Cyclin/CDK pathway inhibitor; Inhibits CDK1 and CDK2

Tryosine kinase inhibitor and epigenetic modifier; Inhibits PDGF, FGF, EGF, TGFß, SIRT1, and SIRT5

Non-muscle myosin II (NM II) ATPase inhibitor

Ubiquitin-proteasome inhibitor; NF-kB pathway inhibitor; I?B activator

PI3K/AKT pathway inhibitor; Inhibits COX-1 and COX-2

Inhibits glycogen synthase kinase 3ß (GSK3ß)

Prostanoid pathway activator; Inhibits 15-hydroxy PGDH

Epigenetic modifier; Inhibits histone EZH2 lysine methyltransferase