Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Rotavapor® R-300

BUCHI

The new R-300 is the most innovative member of the industry leading Rotavapor® family. The award-winning rotary evaporator meets the highest standards in convenience and versatility. The modular design of Rotavapor® R-300 enables full integration of separate system components to create a rotavapor precisely tailored to individual needs. A central interface offers automated system control for the easiest and simplest instrument…

4.8/5.0
|24 Reviews
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Rotavapor® R-220 Pro: Industrial rotary evaporation

BUCHI

The Rotavapor R-220 Pro product line of 20L rotary evaporators includes four platforms to meet the challenging needs of scale-up and production laboratories: maximal flexibility with the widest range of glass assemblies, high performance for fastest distillation rates, continuous operation with automatic draining and refilling, and a cost-efficient model to cover essential needs.

4.7/5.0
|4 Reviews
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MiSeqDx System

Illumina

The MiSeqDx instrument is the first and only FDA-cleared in vitro diagnostic (IVD) next-generation sequencing (NGS) system. Designed specifically for the clinical laboratory environment, the MiSeqDx instrument offers a small, approximately 4 square feet (0.37 square meters) footprint, an easy-to-follow workflow, and data output tailored to the needs of clinical labs. In addition, the integrated software enables sample trackin…

4.9/5.0
|8 Reviews
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NucSpot Nuclear Stains

Biotium

Cell membrane-impermeant, nuclear-specific counterstains. Suitable for fixed cells or staining dead cells in live cultures. Available in a variety of colors from green to near-infrared (near-IR).

4.7/5.0
|6 Reviews

Syft Tracer

Syft Technologies

Syft Tracer is the next generation of real-time trace gas analysis. It delivers highly sensitivite, reproducible, and quantitative data with unparalleled performance stability.  Syft Tracer is optimized for high-throughput environments where 24/7 operation is the standard. SIFT-MS is built to solve the most difficult analytical challenges faced within a variety of industries and applications.  

5.0/5.0
|1 Review
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DPPIV-Glo™ Protease Assay

Promega Corp.

The DPPIV-Glo™ Protease Assay is a homogeneous, luminescent assay that measures dipeptidyl peptidase IV (DPPIV) activity. DPPIV is a serine protease that cleaves N-terminal dipeptides from polypeptides with L-proline or L-alanine at the penultimate position. The DPPIV-Glo™ Assay provides a proluminescent DPPIV substrate, Gly-Pro-aminoluciferin, in a buffer system optimized for DPPIV and luciferase activities. The addition of a…

4.7/5.0
|1 Review
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ONE-Glo™ Luciferase Assay System

Promega Corp.

The ONE-Glo™ Luciferase Assay System provides a highly sensitive, robust, homogeneous assay for detection of firefly luciferase reporter gene expression in mammalian cells. Ideally suited for high- and ultrahigh-throughput applications, the ONE-Glo™ Assay contains a new luciferase substrate, resulting in a reagent that is more stable, more tolerant to sample components, and has less odor than standard luciferase assay reagents…

4.8/5.0
|4 Reviews
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ApoTox-Glo™ Triplex Assay

Promega Corp.

The ApoTox-Glo™ Triplex Assay combines three assay chemistries to easily assess viability, cytotoxicity and apoptosis events in the same cell-based assay well. First, viability and cytotoxicity are determined by measuring two differential protease biomarkers simultaneously with the addition of a single nonlytic reagent containing two peptide substrates. The live-cell protease activity is restricted to intact viable cells and i…

4.6/5.0
|3 Reviews
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Griess Reagent System

Promega Corp.

The Griess Reagent System measures nitrite (NO2–), which is one of two primary stable and nonvolatile breakdown products of nitric oxide (NO). Nitric oxide is an important physiological messenger and effector molecule in many biological systems, including immunological, neuronal and cardiovascular tissues. This assay relies on a diazotization reaction that was originally described by Griess in 1879. Through the years, many mod…

4.7/5.0
|1 Review
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QuantiFluor™ RNA System

Promega Corp.

The QuantiFluor™ RNA System contains a fluorescent RNA-binding dye that enables sensitive quantitation of small amounts of RNA in solution. Detecting and quantitating small amounts of RNA is a very important step used in many biological applications, particularly in molecular biology techniques. These include measuring yields of in vitro transcribed RNA and measuring RNA concentrations before performing Northern blot anal…

4.7/5.0
|5 Reviews
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ROS-Glo™ H2O2 Assay

Promega Corp.

The ROS-Glo™ H2O2 Assay is a homogeneous, fast and sensitive bioluminescent assay that measures the level of hydrogen peroxide (H2O2), a reactive oxygen species (ROS), directly in cell culture or in defined enzyme reactions.   This assay allows identification of conditions or test compounds, such as small molecule inhibitors or inducers, that alter ROS levels. The scalable multiwell format couples a stable luminescent si…

5.0/5.0
|2 Reviews
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Trypsin/Lys-C Mix, Mass Spec Grade

Promega Corp.

Trypsin/Lys-C Mix, Mass Spec Grade, is a mixture of Trypsin Gold, Mass Spectrometry Grade, and rLys-C, Mass Spec Grade. The Trypsin/Lys-C Mix is designed to improve digestion of proteins or protein mixtures in solution.   Using the conventional trypsin digestion protocol (i.e., overnight incubation at nondenaturing conditions), Trypsin/Lys-C Mix improves protein digestion by eliminating the majority of missed cleavages,…

5.0/5.0
|2 Reviews
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Primary and Secondary Antibodies

Promega Corp.

Polyclonal secondary antibodies raised in goat, rabbit or donkey, immunoaffinity-purified using corresponding immobilized antigens and conjugated to horseradish peroxidase (HRP) enzyme.   The Anti-Human IgG (H+L), HRP Conjugate, Anti-Mouse IgG (H+L), HRP Conjugate and Anti-Rabbit IgG (H+L), HRP Conjugate antibodies bind to both heavy and light chains for all IgG subclasses. As with all antibodies, in certain applications…

5.0/5.0
|2 Reviews
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Sequencing Grade Modified Trypsin

Promega Corp.

Trypsin is a serine protease that specifically cleaves at the carboxylic side of lysine and arginine residues.   The stringent specificity of trypsin is essential for protein identification. Native trypsin is subject to autolysis, generating pseudotrypsin, which exhibits a broadened specificity including a chymotrypsin-like activity. Such autolysis products, present in a trypsin preparation, would result in addition…

4.5/5.0
|5 Reviews
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LigaFast™ Rapid DNA Ligation System

Promega Corp.

The LigaFast™ Rapid DNA Ligation System is designed for the efficient ligation of sticky-ended DNA inserts into plasmid vectors in just 5 minutes (blunt-ended inserts in as little as 15 minutes).   Rapid ligation is based on the combination of T4 DNA Ligase with a unique 2X Rapid Ligation Buffer to speed up and streamline your cloning experiments. The LigaFast™ System is designed to eliminate any further purification pri…

4.7/5.0
|2 Reviews
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ViaFect™ Transfection Reagent

Promega Corp.

ViaFect™ Transfection Reagent allows high-efficiency transfection of a wide range of cell types, including iPS Cells, without compromising cell viability.   ViaFect™ Transfection Reagent enables the design of biologically relevant assays in workhorse adherent cell models, suspension cells important for studying cell signaling, and even differentiated cell lines derived from stem cells. ViaFect™ Transfection Reagent offer…

4.9/5.0
|4 Reviews
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GloMax® Discover Microplate Reader

Promega Corp.

This ready-to-use multimode detection system includes: high-performance luminescence, fluorescence, UV-Visible absorbance, BRET and FRET, two-color filtered luminescence and kinetic measurement capabilities.   The GloMax® Discover System is a high-performance multimode detection instrument developed with Promega reagent chemistries to provide a simple means of detecting advanced chemistries. This instrument provides…

4.8/5.0
|8 Reviews
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ADP-Glo™ Kinase Assay

Promega Corp.

ADP-Glo™ Kinase Assay is a luminescent kinase assay that measures ADP formed from a kinase reaction; ADP is converted into ATP, which is converted into light by Ultra-Glo™ Luciferase.   The luminescent signal positively correlates with kinase activity. The assay is well suited for measuring the effects chemical compounds have on the activity of a broad range of purified kinases, making it ideal for both primary scre…

5.0/5.0
|2 Reviews
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