Yokogawa Fluid Imaging Technologies, Inc Drug discovery > Target Discovery Products & Reviews

Through its exceptional image quality and the widest size range available, FlowCam® 8000 represents state-of-the-art particle imaging technology. Analyze thousands of particles in less than a minute and comprehensively characterize the size, count, morphology, and identity of subvisible and visible particulates in their native solvent.

FlowCam® Nano provides dynamic image analysis of submicron particles from 300 nm to 2 µm, bridging the gap between traditional flow imaging microscopy and other particle analysis techniques. Use FlowCam Nano for early detection of aggregates and contaminant monitoring for protein formulations, nano-drug delivery systems, characterization of bacteria, bioprocess monitoring, and materials characterization.

The ALH for FlowCam™ Automated Liquid Handling system integrates with FlowCam 8000 series instruments, FlowCam LO, and FlowCam Cyano to automate sample handling and FlowCam operation. ALH for FlowCam minimizes the risk of human error and improves measurement repeatability, ensures safer lab operation, and increases productivity.

VisualSpreadsheet® is a powerful software program capable of setting up analysis methods, acquiring data, and processing images captured with FlowCam.

Innovative particle characterization with FlowCam® LO combines flow imaging microscopy (FIM) and light obscuration (LO) into a single analytical solution. Beyond the compendial light obscuration method to fulfill USP <787> and <788> requirements, flow imaging microscopy provides an orthogonal method for quality control of subvisible particulate matter.

VisualAI™, an add-on module for VisualSpreadsheet 6, is a pre-trained, AI-driven image analysis module that recognizes images of biopharmaceutical aggregates captured on any FlowCam 8100 or FlowCam LO instrument. VisualAI is a powerful tool for quantifying protein aggregate and silicone oil droplet content in protein-based drug products.