Over the years, YMC constantly has increased its international exposure to innovative marketplaces. Products and services have matured to a level of world-wide recognition, specifically in the area of pharmaceutical and biotech compounds, where YMC is one of the few companies to fully support normal phase and reversed phase chromatography techniques from analytical to process scale, throughout the entire lifetime of a compound from R&D to scale-up, production and Quality Control. Substantial investments into facilities and staff represent YMC’s ongoing commitment towards high quality products and technical support: in Komatsu/Japan, new premises provide equipment for professional industrial-scale custom purification services, for example, and organic synthesis facilities under GMP-conditions, where applicable. Chromatography Division The presence of qualified and dedicated support networking ensures not only worldwide availability of product, but also the ability to provide meaningful practical assistance with regard to method development, method transfer and method validation – locally, personally and efficiently. It is not only product specifications that represent YMC quality, but the perceived ethical values of having people happily provide competent and consistent performance together with pronounced reliability even for difficult and demanding separations– day after day, year after year. The European network consists of highly focused product specialist teams, based near Düsseldorf in Germany, to provide active support for chromatographers and local representatives or distributors; extensive inventory ensures speedy supply of product. Mission Statement As a mission statement, it is our ambition to provide chromatographic solutions for any compound from its discovery through scaling-up into production and its final quality control in the lab. Whether random R&D, combinatorial chemistry or high-throughput screening, LC-MS, automation, capillary columns with high sensitivity or process-scale engineering: YMC can be relied upon to provide positive support, chromatographic tools and assistance.
Highly robust (U)HPLC columns for BioLC which are stable towards pH and temperature. Different pore sizes are available for the analysis of peptides, proteins, antibodies and oligonucleotides.
This new strong anion exchange resin offers an optimised macro-porous structure that ensures an efficient purification of large biomolecules, such as adeno-associated viruses (AAVs) and plasmid DNA (pDNA). With its high binding capacity for such molecules and high separation efficiency even at elevated flow rates, MacroSep IEX Q is a perfect addition to DSP platforms.
Bioinert coated YMC Accura BioPro IEX columns provide excellent peak shapes for sensitive compounds, ensuring high recovery from the very first injection.
Coated and immobilized CHIRAL ART polysaccharide columns by YMC offer wide selectivity range, high stability and attractive pricing.
YMC-Actus prepacked (semi-)preparative HPLC columns show high stability and long lifetimes even under high flow rates and steep gradient conditions without any void volume formation.
Capillary columns available with every fully porous RP/NP/HILIC phase from YMC for high sensitivity analyses. Compatible with nearly all Nano-/MicroLC/MS systems due to two different connection sizes (1/16" and 1/32").
BioPro IEX, YMC's strong ion exchange material are based on a hydrophilic polymer which provides low non-specific adsorption and high recoveries. Porous and non-porous polymer beads are available for high loadability and throughput.
YMC provides silica-based SEC phases with a dihydroxypropyl modification in 4 different pore sizes.
YMC-SEC MAB is a silica-based size exclusion chromatography column utilizing a dihydroxypropyl stationary phase bonded to a silica gel base, specifically designed for antibody separations.
BioPro HIC columns based on non-porous hydrophilic polymer beads and functionalised with butyl chains are optimised for the analysis of antibodies, antibody-drug conjugates (ADCs) and other proteins.
With YMC-Triart Prep, pH stable preparative HPLC stationary phases are available for industrial-scale applications. This hybrid silica-based material can be used in a pH range of 2.0 - 10.0 and allows more efficient cleaning procedures. The innovative YMC-Triart Prep combines mechanical strength and pH stability.
From laboratory to pilot scale, YMC offers reliable, high quality glass columns for all kind of application areas.
YMC PilotPLUS columns are completely biocompatible and characterised by safe and easy handling.
Does your application require customised pilot columns? With YMC Pilot columns, customised versions can be constructed to address your needs. Of course standard dimensions are available, too!
BioPro IEX and BioPro IEX SmartSep resins are specifically designed for biochromatography. They are available as a strong anion exchanger (BioPro IEX Q) and a strong cation exchanger (BioPro IEX S). The resins are based on a hydrophilic polymer matrix, with a particle size of 10 µm, 20 µm, 30 µm and 75 µm.
1 mm UHPLC columns are available in different lengths packed with the highly robust 1.9 µm YMC-Triart C18 particles.
Bioinert YMC Accura Triart RP and HILIC columns are available for the analysis of critical substances including selected proteins, (oligo)nucleotides and metal-coordinating compounds such as organophosphates.
Highly robust hybrid silica material for the purification of proteins, peptides and oligonucleotides, which combines mechanical strength and pH stability. The larger pore size makes YMC Triart-Prep Bio200 C8 the ideal choice for the purification of mid-size to large biomolecules.
