UCT, Inc. Drug discovery > Lead Discovery Products & Reviews

The QuEChERS Clean-up step is rapidly completed using the QuICK QuEChERS cartridge. This self-contained cartridge contains 110 mg of anhydrous MgSO4 and 180 mg of PSA. Placed on the end of a disposable syringe, the QuEChERS extract is pushed through directly into a sample vial for analysis. Clean-up is equivalent to dSPE clean-up, but faster and easier, eliminating the need for centrifugation.

Pre-packed 6 ml anion exchange SPE cartridges are made to the exact specification of EPA Method 548 to assure high capture efficiency and consistent results for excellent analytical reproducibility.

Clean, activated, and ready-for-use, 30 mesh copper granules remove unwanted elemental sulfur from pesticide and PCB extracts. Granules are much easier to use than copper powder or TBA and eliminate the need for toxic mercury.

Chlorophyll in QuEChERS extracts must be removed to reduce potential instrument downtime. This is removed from extracts using graphitized carbon black (GCB) Unfortunately, GCB also removes planar analytes reducing analytical accuracy. ChloroFiltr®, used in place of GCB in dSPE tubes, removes unwanted chlorophyll without removing pesticides or environmental analytes. No change in procedure are required.

When clean plastic cartridges are not clean enough. 6 mL glass SPE cartridges can be packed with your choice of UCT sorbent using PTFE frits and individually sealed in certified Mylar for purity.

Enviro-Clean 500mg/6mL cartridge PSDVB w/Polyethylene frits. It is used with EPA Methods 526, 527, 528, 529 and 8330.

Clean Screen® DAU Solid Phase Extraction Column is the flagship product of the forensic solid phase extraction column line. The first product of its kind in the industry, it is a mixed-mode column exhibiting both hydrophobic and cation exchange characteristics. Over 20 years of experience has shown this column to be effective on hundreds of drugs in both the acid-neutral and basic drug categories.

The Clean Screen® XCEL Solid Phase Extraction Columns are a line of sample prep phases designed to reduce the number of steps in the extraction, and therefore the amount of time and solvent necessary to complete the sample cleanup. Further advantages include reduced sample size and improved cleanliness and recovery. The Xcel I column will extract a wide array of basic drugs including benzodiazepines and opiates. The Xcel II co…

Select pH Buffer Pouches - UCT has developed a line of premeasured “ready-to-use” phosphate and acetate buffer pouches. These pouches contain the correct quantity of reagent to quickly and accurately prepare buffers at the correct pH and concentration to simplify solid-phase extraction methods.

These cartridges are designed to meet large volume, real world samples. The frits and sorbent bed resist plugging, the format fits several types of manual and automated extraction systems. Various bonded phases available including C18, C8, DVB, & graphitized carbon black.

QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) is a sample extraction and clean-up technique used for the analysis of multiple pesticide residues in agricultural products. UCT manufactures a wide variety of pre-filled tubes and reagent pouches for all QuEChERS method variations including PSA, C18, buffers, anh. MgSO4, NaCl, ChloroFiltr, and carbon.

The Clean Screen® FASt column is a novel approach to improved sample preparation for LC/MS analysis. The column employs a one step process to prepare urine samples for analysis of multiple drugs and metabolites. By quickly and efficiently reducing the amount of unwanted matrix and particulates in the final sample, the analysis can proceed with less chance of matrix suppression and LC column clogging.

Clean Screen® Xcel Well Plates The Clean Screen Xcel products are a line of sample prep phases designed to reduce the number of steps in the extraction, and therefore the amount of time and solvent necessary to complete the sample cleanup. Further advantages include reduced sample size and improved cleanliness and recovery. The Xcel I well plate will extract a wide array of basic drugs including benzodiazepines and opiates.…

Positive Pressure Manifold - A simple, robust way to quickly process up to 48 samples at one time. The Positive Pressure Manifold can accommodate a multitude of column sizes and provides even flow to each position. Positive Pressure Manifold Features: All 48 positions are individually regulated to provide even pressure to each column. There are four banks of 12 positions each. The user can control flow to each of the four…

Styre Screen® Extraction Columns contain an ultra clean, highly cross-linked styrene and divinylbenzene copolymer. The Styre Screen particles have an average particle size of 30 microns and a very high analyte capacity making them ideal for standard solid phase extraction applications. The increased analyte capacity means that less sorbent bed mass is needed which results in faster flow rates and less solvent use. Higher th…

SELECTRA-SIL® Derivatizing Reagents SELECTRA-SIL® is an extensive line of derivatizing reagents manufactured by UCT at its facility in Bristol, PA. Our reagents are designed to increase molecular weight, lower boiling points, and create a more specific ion for compounds intended for gas chromatography and GC/MS. SELECTRA-SIL® Derivatizing Reagents Benefits: Improved chromatographic resolution - increased volatility - red…

Our 96 Deep Well Plates are made from solvent resistant, low extractable polypropylene. Standard frits are polyethylene with 20μm pores. The 2mL well provides capability for methods that require a larger sample size. The separate wells and greater capacity eliminate well-to-well carry over. We offer disposable plates compatible with Beckman, Caliper, Gilson, Hamilton, PerkinElmer and Tecan liquid handling systems. 96 Deep Wel…

The FASt Well Plate is a novel approach to improved sample preparation for LC/MS analysis. The well plate employs a one step process to prepare urine samples for analysis of multiple drugs and metabolites. By quickly and efficiently reducing the amount of unwanted matrix and particulates in the final sample, the analysis can proceed with less chance of matrix suppression and LC column clogging.

Endcapped C18 - Enviro Clean SPE Cartridges Enviro-Clean® cartridges are designed for use by analysts that demand a clean, dependable and rugged product for low level environmental analyses. Our EC SPE Cartridges run the gambit of our sorbents for every configuration you require. C18, Octadecyl Hydrophobic, 1000 mg/6 mL. Part # EEC181M6

These sorbents are composed of a silica backbone bonded with hydrocarbon chains. They are used to extract compounds, which exhibit non-polar or neutral characteristics, from complex matrices. The C18 phase is the most popular phase.  UCT offers a range of hydrocarbon chain lengths from C2 to C30. In addition, we offer isobutyl, tertbutyl, phenyl, and cyclohexyl bonded phases.

Compounds are retained on hydrophilic sorbents through polar interactions including hydrogen bonding, pi-pi or dipole-dipole interaction.  Compounds typically extracted on a hydrophilic column include analytes which have polar groups, including amines, hydroxyls and carbonyls. Elution is performed by strong polar solvents. For these types of extractions UCT offers various types of base silica, Florisil®, Alumina's, cyanopropy…

This sorbent is composed of a silica backbone bonded with a carbon chain terminated by a negatively or positively charged functional group. Ion exchange interactions occur between a sorbent that carries a charge and a compound of opposite charge. This electrostatic interaction is reversible by neutralizing the sorbent and /or analyte. Ion exchange bonds can also be disrupted by introduction of a “counter ion” to compete with…

This sorbent is composed of a silica backbone bonded with a carbon chain terminated by a negatively or positively charged functional group. Ion exchange interactions occur between a sorbent that carries a charge and a compound of opposite charge. This electrostatic interaction is reversible by neutralizing the sorbent and /or analyte. Ion exchange bonds can also be disrupted by introduction of a “counter ion” to compete with…

The same clean polypropylene tubes we use in our own column assemblies are available as an empty tube. Available in 1mL through 150mL tube sizes. The flange on the lip means the columns are suitable for use with UCT's positive pressure manifold as well as with vacuum manifold systems.

Complete Vacuum Manifold System includes a glass block, Corian® manifold lid, a cover gasket, a vacuum gauge and valve assembly, teflon tips (16 or 24), an adjustable collection rack, bulkhead luer fittings, plugs (16 or 24), and manifold safety tray.