SomaLogic Drug discovery > Target Discovery Products & Reviews

The SomaScan™ 11K Assay Services employ a highly multiplexed, sensitive, quantitative, and reproducible proteomic platform that profiles up to 11,000 human protein measurements in diverse sample types and species – without enrichment or depletion. Ideal for biomarker discovery, it supports basic, translational, pre-clinical, and clinical research across a wide range of diseases.

KREX™ i-Ome™ Discovery Services enable highly multiplexed autoantibody profiling for rapid, reproducible discovery across diverse diseases. The platform measures antibody binding to 1,800+ full-length, correctly folded human proteins – preserving conformational epitopes for highly specific and biologically relevant autoantibody detection. It provides valuable insight into immune responses in health, disease and treatment.

Bioinformatics and Protein Array Services

Profiling against cancer antigens. Using the CTA Protein Array, Sengenics can quantify autoantibodies against more than 200 clinically relevant cancer testis antigens. These are tumor antigens normally expressed in germ cells but not in adult somatic tissues. In cancers, this regulation can be disrupted, resulting in CTA expression in tumors. The CTA array is ideal for research related to cancer immunotherapy.

Autoimmune disease autoantibody screening. Using the Pan-Autoimmune Protein Array 1.0, Sengenics can screen autoantibodies against more than 100 clinically relevant antigens in a wide range of autoimmune diseases. The Pan-Autoimmune Protein Array 1.0 service is ideal for focused autoimmune disease research.

- Parallel screening of multiple samples on one slide - Proteins can be selected from our existing library or can be custom made - Choose from 2, 4, 8 or 16-plex format - Bespoke content and project design service

- Parallel screening of multiple samples on one slide - Proteins can be selected from our existing library or can be custom made - Choose from 2, 4, 8 or 16-plex format - Bespoke content and project design service

- Parallel screening of multiple samples on one slide - Proteins can be selected from our existing library or can be custom made - Choose from 2, 4, 8 or 16-plex format - Bespoke content and project design service

- Parallel screening of multiple samples on one slide - Proteins can be selected from our existing library or can be custom made - Choose from 2, 4, 8 or 16-plex format - Bespoke content and project design service

Cancer drug screening and discovery. The OncoRex p53 Cancer Array provides a biologically relevant screening tool since all p53 variants are correctly folded and functional using the patented KREX ® protein folding technology. Using the array, Sengenics can screen your therapeutic antibodies and protein binding compounds against more than 100 p53 wildtype and mutant variants by measuring their impact on DNA binding as a func…

The i-Ome Discovery Protein Array uses the patented KREX® protein folding technology to enable accurate and reproducible profiling of patient samples against more than 1800 carefully selected full-length, properly folded proteins. Curated content focused on known and potential autoantigens helps facilitate biomarker discovery with significantly lower false discovery rates and smaller sample sizes than other technologies. The…