Thermo Scientific™ Multiskan™ Skyhigh Microplate Spectrophotometer
State-of-the-art touchscreen, cloud-connected microplate spectrophotometer with built-in protocols for common assays such as nucleic acid and protein analysis. Comes with intuitive Thermo Scientific SkanIt Software.

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Strong, reliable and accurate
Biotechnology- Antimicrobial, Spectrum analysis
The Multiskan spectrophotometer is actually what they say it is. Reliable, ease to use, sensitive and fast. No need to always troubleshoot or call vendors for repairs. It’s value for the money.
Review Date: 26 Nov 2025 | Thermo Fisher Scientific
Simple to use and reliable.
Cytotoxicity
As far as simplicity goes, this spectrophotometer is hard to beat. For day-to-day use with or without a connected pc compared to our old spectrophotometer it excels at readout speed and assay setup. We mainly use it for endpoint cytotoxicity assay analysis and protein / DNA content analysis (thanks to a handy μDrop plate). High readout accuracy is expected from a modern spectrophotometer and in this department, it also does not disappoint. The software is also very clear and intuitive (the same as in the Varioskan lux) but for fast and simple tasks we often use the integrated LCD screen. This device is also very easy to use for beginner users, even our students can use it without an issue within 15 minutes of training.
Review Date: 27 Sept 2021 | Thermo Fisher Scientific
Small and efficient!
ELISA, absorbance
The unit is easy to use and can be connected with third-party software.
Review Date: 28 Jun 2019 | Thermo Fisher Scientific
Exceptional user experience delivered by a state-of-the-art microplate spectrophotometer
The Thermo Scientific™ Multiskan Sky™ Microplate Spectrophotometer is a UV/Vis microplate spectrophotometer designed to be convenient and easy to use for virtually any photometric research application, especially DNA, RNA and protein analysis. It is ideal for multi-user environments where a variety of endpoint, kinetic and spectral assays are performed. Multiskan Sky instruments are available in three different configurations. Touch screen models offer the flexibility to use the stand-alone instrument or in conjunction with Thermo Scientific SkanIt PC software. The Multiskan Sky model operated solely via SkanIt software is ideal for users who rely on a PC for all operations. Cuvette reading capability is also offered in some models.
Features:
- Multiple measurement modes including end-point, kinetic, spectral scanning 200-1000nm
- Fast, easy microvolume measurements for nucleic acid and protein samples with the Thermo Scientific™ µDrop™ Plate
- Simple-to-use software enables experiment set up in minutes
- Vaidated, pre-built protocols with real data and calculations available in SkanIt Cloud Library
- Access and manage data remotely with the ability to save and open files from anywhere and connection to Thermo Fisher Connect
- Fast read speeds: reads a 96-well plate in six seconds
The best tools for DNA and RNA quantification
Nucleic acid quantification (NAQ) determines the concentration of DNA or RNA in a sample, enabling the calculation of the correct amount of nucleic acid required for downstream applications. Using the correct amount of nucleic acid saves time and money, preventing downstream experimental failures, and ensures data quality. Discover how to select the most suitable technology for optimal nucleic acid input, and explore how solutions from Thermo Fisher Scientific offer reliable experimental outcomes, and can help to avoid issues like insufficient amplification or poor sequencing results.
Accelerate detection, eclipse SARS-CoV-2
In this application note, Thermo Fisher Scientific demonstrate how the Invitrogen™ Human SARS-CoV-2 Spike (Trimer) Ig Total ELISA Kit, along with the Thermo Scientific™ Multiskan™ SkyHigh Microplate Spectrophotometer, can provided a sensitive and specific solution for detecting and quantifying the presence of antibodies against SARS-CoV-2 in research samples.
Simplified workflow for Instant ELISA kits using the Multiskan Sky Microplate Spectrophotometer and Wellwash Versa Microplate Washer
In this application note, Thermo Fisher Scientific demonstrates the benefits of using the Invitrogen™ Human TNFα Instant ELISA™ Kit with the Thermo Scientific™ Multiskan™ Sky Microplate Spectrophotomer and Wellwash™ Versa™ Microplate Washer. In addition, Thermo Fisher Scientific shows how to streamline the workflow by incorporating a preprogrammed pipetting protocol developed with the My Pipette™ Creator app and a Thermo Scientific™ E1-ClipTip™ Bluetooth™ electronic pipette.
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