Multidrop™ Pico™ 1 and Pico™ 8 Digital Dispenser
Simplify assay set up while saving on compounds, reagents and time with the new Thermo Scientific™ Multidrop™ Pico™ 1 and Pico™ 8 Digital Dispensers

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The new Thermo Scientific™ Multidrop™ Pico™ 1 and Pico™ 8 Digital Dispensers offer precise dispensing with volumes between 11pL and 10µL. With it’s easy to use PicoIT software and ability to dispense drug compounds researchers can quickly and easily create drug dose response and drug synergy experiments (combine this functionality with the Thermo Scientific™ Multidrop™ Combi’s cell dispensing capability for a more complete drug synergy dispensing solution). In other applications, miniaturize qPCR reaction volumes, using ten times less sample and reagent than traditional methods, as low as 11pL or eliminate the manual task of serial dilution and improve accuracy and precision while saving reagent costs.
The digital dispenser supports a wide range of applications and sample-types:
- Drug combination studies
- qPCR
- DMPK
- Assay development
- Biochemical assays
- Secondary screening
- Cell-based assays
- Spotting
- Enzyme profiling
- Synthetic biology
- Antibody therapies
Improved Efficiency and Speed
The digital dispenser offers 40 times greater speed than analog serial dilution – from 10 minutes to just 15 seconds – eliminating precious time and accelerating your research.
The digital dispenser offers 40 times greater speed than analog serial dilution – from 10 minutes to just 15 seconds – eliminating precious time and accelerating your research.
Next-gen liquid dispensing from microliters to picoliters
Aaron Kettle, Senior Product Manager at Thermo Fisher Scientific, presents two automated liquid handling systems: the Multidrop™ Combi+ Reagent Dispenser and the Multidrop™ Pico™ 8 Digital Dispenser.
The Multidrop™ Combi+ delivers fast, microliter-level dispensing for reagents and cell lines into well plates, ensuring high-speed, efficient workflows. Meanwhile, the Multidrop™ Pico™ 8 is designed for ultra-precise, low-volume liquid handling, making it ideal for applications requiring accuracy at the picoliter scale.
Both systems are tailored for the pharmaceutical and biotech industries, offering reliable performance, intuitive software, and seamless automation to enhance efficiency and reproducibility in the lab.
This video was filmed at SLAS2025.



















