LenS3 MALS and MALS-V Multi-Angle Light Scattering Detector Series
The LenS3 MALS detector offers a revolutionary approach for the measurement of molecular weight (MW) and radius of gyration (Rg) of synthetic polymers, polysaccharides, proteins, and biopolymers. A novel optical design, a unique cell-block assembly, and a new calculation methodology make the LenS3 MALS detector the first groundbreaking innovation in the light scattering technology arena in decades!

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The LenS3 MALS detector offers a revolutionary approach for the measurement of molecular weight (MW) and radius of gyration (Rg) of synthetic polymers, polysaccharides, proteins, and biopolymers. A novel optical design, a unique cell-block assembly, and a new calculation methodology make the LenS3 MALS detector the first groundbreaking innovation in the light scattering technology arena in decades! The new member of the LenS3 family, the LenS3 MALS-V dual detector, is the first integrated light scattering and viscometry dual detector. Combined with the EcoSEC Elite GPC system and TSKgel columns, it offers a complete, cost-effective, high-performance approach for triple detection GPC.
Featuring a patent pending cell geometry and a lower wavelength laser (at 514 nm), the LenS3 MALS detector allows direct measurement of molecular weight and provides best-in-class sensitivity. In addition, with an improved normalization process and a new method for utilizing the angular dependence, the determination of radius of gyration of smaller macromolecules below 10 nm in gyration size, Rg, is now possible for the first time in history!
The LenS3 MALS and LenS3 MALS-V detectors are driven by SECview™ software, capable of GPC system/hardware control, multi-channel data acquisition, data processing and analysis. Totally focused around enhancing the user-interface experience, SECview is a welcoming fresh perspective that streamlines the complex calculations required by the advanced detectors and is the only GPC/SEC data processing module today that performs analysis of sample-of-interest using multiple calibration methods simultaneously.
Brochures
A new paradigm in light scattering technology
In this product brochure, Tosoh Bioscience showcases its comprehensive suite of instruments, columns, and software tailored for the thorough characterization of biopharmaceutical macromolecules, sustainable polymers, and common engineering plastics. The TSKgel® GPC/SEC columns have been designed to offer high resolution, excellent reproducibility, and long column life, catering to a wide range of GPC/SEC applications. The LenS™3 multi-angle light scattering (MALS) detectors provide a method for measuring molecular weight and size distributions of various biomolecules and polymers, powered by user-friendly SECview™ software. Additionally, the EcoSEC™GPC systems offer fully automated solutions for gel permeation chromatography, ensuring robust polymer analysis with the highest reproducibility, incorporating advanced features like dual pump solvent systems and efficient refractometry detection.
Decoding the structure of natural polymers with advanced GPC/SEC
In this video from Tosoh, learn more about different polymer properties and their associated parameters. Discover how triple detection can be used for the full characterization of polysaccharides, and explore how gel permeation chromatography with refractive index and light scattering detection can be used to identify necessary parameters.
Advancements in materials characterization: From decoding polymers and battery materials to harnessing the power of atomic force microscopy
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