expression® Compact Mass Spectrometer (CMS)
The expression® CMS integrates with nearly every chemistry technique from the simplest, fastest direct probe analysis requiring no sample preparation to ultra-high performance compound separation with LC integration.
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Excellent, reliable instrument for the price.
Research and development
This instrument is simple to use and maintain. It is particularly good for those researchers that may have only periodic use. It can be shut down at the end of a work day and started up the next day and be ready to operate within about 45 minutes if a tune is required or as in little as 30 minutes if no tuning is required. This makes the operation of the device much more cost effective than other systems that must run 24/7, 365. Multiple ion sources exist for a range of different types of analytes and for different sample introduction needs. It is nominal mass resolution, but holds a calibration very well. Tandem mass spectrometry would be really nice but confirmation of pure compounds infused or eluting can be done with alternating scans with different interface conditions that either promote intact molecules or fragmentation in the interface. One can also alternate positive ion and negative ion scans which provides a wider range of detection capability in a single run.
Review Date: 10 Mar 2025 | Advion Interchim Scientific
The family of expression® CMS was developed with maximum versatility in mind allowing users to switch rapidly between various sample introduction techniques with little sample preparation. The affordability, small size, and ease of use make them ideal for a variety of applications.
Most laboratories require the ability to analyze a range of samples using more than one technique for more complete identification and characterization of samples. The expression® CMS offers the most versatile sample techniques on the market, including:
• Plate Express™ TLC Plate Reader
• Atmospheric Solids Analysis Probe (ASAP®)
• inert Atmospheric Solids Analysis Probe (iASAP)
• Touch Express™ Open Port Sampling Interface (OPSI)
• Volatile APCI (vAPCI)
• AVANT™ Modular (U)HPLC
• Direct Injection/Flow Injection Analysis (FIA)
• Flow Chemistry
• Flash Chromatography
• Preparative Liquid Chromatography (Prep-LC)
• Supercritical Fluids Chromatography (SFC)
Advion Interchim Scientific's unrivalled expertise in mass spectrometry has created this solution just for chemists. Whether you are a biopharmaceutical company, academic teaching/research lab, or any industry requiring routine mass assays, the expression® CMS delivers high performance in a compact, easy-to-use package at an affordable price.
Analyze your compounds faster than LC/MS with TLC/MS
Plate Express™ is a device that provides a simple, automated means of obtaining mass spectra directly from TLC plates, combined with the Advion Interchim Scientific® expression® CMS (compact mass spectrometer) creating a technique known as TLC/CMS. Using this technique chemists can quickly and confidently identify products even in complex mixtures without additional sample preparation. This whitepaper explores the use of TLC/CMS as an alternative chromatography technology for faster, more efficient analysis over traditional LC/MS runs.
Intelligent flash purification using TLC and mass spectrometry
The compound synthesis, purification and confirmation process often presents challenges throughout. From ensuring successful synthesis of your product, setting up a flash purification method, and finally confirming ID of fractions, the lengthy work flow can be time consuming and repetitive. In this application note, Advion demonstrates a new work flow that offers seamless steps to quickly and easily drive the process from reaction monitoring to flash purification and fraction ID.
